APOA4 Polyclonal Antibody | MyBioSource MBS9129369 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

APOA4 Polyclonal Antibody

catalog :

MBS9129369

quantity :

0.05 mL

price :

200 USD

clonality :

polyclonal

host :

unidentified

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of extracts of various cell lines, using APOA4 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

product information

catalog number :

MBS9129369

products type :

Antibody

products full name :

APOA4 Polyclonal Antibody

products short name :

[APOA4]

other names :

[Apolipoprotein A-IV; Apolipoprotein A-IV; apolipoprotein A-IV; apolipoprotein A-IV; Apolipoprotein A4]

products gene name :

[APOA4]

other gene names :

[APOA4; APOA4; Apo-AIV; ApoA-IV]

uniprot entry name :

APOA4_HUMAN

clonality :

polyclonal

isotype :

IgG

host :

unknown

reactivity :

Human, Mouse, Rat

sequence length :

396

purity :

Affinity purification

storage stability :

Store at -20 degree C. Avoid freeze / thaw cycles.

tested application :

Western Blot (WB)

app notes :

WB: 1:500 - 1:2,000

image1 heading :

Western Blot (WB)

other info1 :

Category: Primary Antibody. Source: Rabbit. Immunogen: Recombinant protein of human APOA4.

other info2 :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

products categories :

Polyclonal

products description :

Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.

ncbi gi num :

93163358

uniprot acc num :

P06727

ncbi mol weight :

Calculated MW: 45kDa. Observed MW: refer to figures

ncbi pathways :

Amyloid Fiber Formation Pathway (1269169); Chylomicron-mediated Lipid Transport Pathway (1270006); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Lipid Digestion, Mobilization, And Transport Pathway (1270002); Lipoprotein Metabolism Pathway (1270005); Metabolism Pathway (1269956); Metabolism Of Fat-soluble Vitamins Pathway (1339147); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Metabolism Of Proteins Pathway (1268677)

ncbi summary :

uniprot summary :

APOA4: May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. Synthesized primarily in the intestine and secreted in plasma. Belongs to the apolipoprotein A1/A4/E family. Protein type: Secreted, signal peptide; Cell adhesion; Endoplasmic reticulum; Lipid-binding; Secreted. Chromosomal Location of Human Ortholog: 11q23. Cellular Component: cell surface; chylomicron; cytosol; early endosome; endoplasmic reticulum lumen; extracellular region; extracellular space. Molecular Function: antioxidant activity; cholesterol binding; cholesterol transporter activity; copper ion binding; lipid binding; lipid transporter activity; phosphatidylcholine binding; protein binding; protein homodimerization activity. Biological Process: cellular protein metabolic process; cholesterol biosynthetic process; cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; fat-soluble vitamin metabolic process; hydrogen peroxide catabolic process; innate immune response in mucosa; leukocyte adhesion; lipid homeostasis; lipid transport; lipoprotein metabolic process; multicellular organismal lipid catabolic process; neurite regeneration; phosphatidylcholine metabolic process; phospholipid efflux; phototransduction, visible light; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity; protein-lipid complex assembly; regulation of cholesterol absorption; regulation of cholesterol transport; removal of superoxide radicals; response to lipid hydroperoxide; retinoid metabolic process; reverse cholesterol transport; triacylglycerol catabolic process; vitamin metabolic process

size1 :

0.05 mL

price1 :

200 USD

size2 :

0.1 mL

price2 :

275

size3 :

0.2 mL

price3 :

430

more info or order :

MyBioSource product webpage