catalog number :
MBS9129349
products full name :
POLE4 Polyclonal Antibody
products short name :
[POLE4]
other names :
[DNA polymerase epsilon subunit 4; DNA polymerase epsilon subunit 4; DNA polymerase epsilon subunit 4; polymerase (DNA) epsilon 4, accessory subunit; DNA polymerase II subunit 4; DNA polymerase epsilon subunit p12]
products gene name :
[POLE4]
other gene names :
[POLE4; POLE4; p12; YHHQ1]
uniprot entry name :
DPOE4_HUMAN
purity :
Affinity purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500-1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant protein of human POLE4. Source: Rabbit. Category: Primary Antibody
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
ncbi acc num :
NP_063949.2
ncbi gb acc num :
NM_019896.2
ncbi pathways :
Base Excision Repair Pathway (83043); Base Excision Repair Pathway (451); DNA Polymerase Epsilon Complex Pathway (413419); DNA Polymerase Epsilon Complex Pathway (890526); DNA Replication Pathway (83039); DNA Replication Pathway (444); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); Metabolic Pathways (132956); Nucleotide Excision Repair Pathway (83044)
ncbi summary :
POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]
uniprot summary :
POLE4: May play a role in allowing polymerase epsilon to carry out its replication and/or repair function. Protein type: EC 2.7.7.7; Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Transferase. Chromosomal Location of Human Ortholog: 2p12. Cellular Component: epsilon DNA polymerase complex; nucleus. Molecular Function: DNA binding; DNA-directed DNA polymerase activity; protein binding; protein heterodimerization activity