product summary
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company name :
MyBioSource
product type :
antibody
product name :
CLEC1B Polyclonal Antibody
catalog :
MBS9129243
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9129243 image 1
Western blot analysis of extracts of various cell lines, using CLEC1B antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
product information
catalog number :
MBS9129243
products type :
Antibody
products full name :
CLEC1B Polyclonal Antibody
products short name :
[CLEC1B]
products name syn :
[CLEC2; CLEC2B; PRO1384; QDED721; 1810061I13Rik]
other names :
[C-type lectin domain family 1 member B isoform b; C-type lectin domain family 1 member B; C-type lectin domain family 1 member B; C-type lectin domain family 1 member B; C-type lectin-like receptor 2; CLEC-2]
products gene name :
[CLEC1B]
other gene names :
[CLEC1B; CLEC1B; CLEC2; CLEC2B; PRO1384; QDED721; 1810061I13Rik; CLEC2; CLEC-2]
uniprot entry name :
CLC1B_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
196
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-196 of human CLEC1B (NP_001092901.1). Calculated MW: 23kDa/26kDa. Observed MW: 27kDa
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).
ncbi gi num :
153252048
ncbi acc num :
NP_001092901.1
ncbi gb acc num :
NM_001099431.1
uniprot acc num :
Q9P126
ncbi pathways :
GPVI-mediated Activation Cascade Pathway (1269357); Hemostasis Pathway (1269340); Platelet Activation, Signaling And Aggregation Pathway (1269350)
ncbi summary :
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
uniprot summary :
CLEC1B: Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 12p13.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: carbohydrate binding; protein binding; transmembrane receptor activity. Biological Process: blood coagulation; cell surface receptor linked signal transduction; defense response; platelet activation; platelet formation
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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