PTPRS Polyclonal Antibody | MyBioSource MBS9129086 product information

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company name :

MyBioSource

product type :

antibody

product name :

PTPRS Polyclonal Antibody

catalog :

MBS9129086

quantity :

0.05 mL

price :

200 USD

clonality :

polyclonal

host :

unidentified

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of extracts of rat testis, using PTPRS antibody at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

product information

catalog number :

MBS9129086

products type :

Antibody

products full name :

PTPRS Polyclonal Antibody

products short name :

[PTPRS]

other names :

[receptor-type tyrosine-protein phosphatase S isoform 1; Receptor-type tyrosine-protein phosphatase S; receptor-type tyrosine-protein phosphatase S; protein tyrosine phosphatase, receptor type S; Receptor-type tyrosine-protein phosphatase sigma; R-PTP-sigma]

products gene name :

[PTPRS]

other gene names :

[PTPRS; PTPRS; PTPSIGMA; R-PTP-S; R-PTP-sigma]

uniprot entry name :

PTPRS_HUMAN

clonality :

polyclonal

isotype :

IgG

host :

unknown

reactivity :

Rat

sequence length :

1948

purity :

Affinity purification

storage stability :

Store at -20 degree C. Avoid freeze / thaw cycles.

tested application :

Western Blot (WB)

app notes :

WB: 1:500 - 1:2,000

image1 heading :

Western Blot (WB)

other info1 :

Source: Rabbit. Immunogen: Recombinant protein of human PTPRS. Category: Primary Antibody

other info2 :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

products categories :

Polyclonal

products description :

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

ncbi gi num :

104487006

ncbi acc num :

NP_002841.3

ncbi gb acc num :

NM_002850.3

uniprot acc num :

Q13332

ncbi mol weight :

217kDa

ncbi pathways :

ECM Proteoglycans Pathway (1270256); Extracellular Matrix Organization Pathway (1270244)

ncbi summary :

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

uniprot summary :

PTPRS: Interacts with LAR-interacting protein LIP.1. Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. 7 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine; EC 3.1.3.48; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: integral to plasma membrane. Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity. Biological Process: cell adhesion; cerebellum development; cerebral cortex development; corpus callosum development; extracellular matrix organization and biogenesis; hippocampus development; spinal cord development

size1 :

0.05 mL

price1 :

200 USD

size2 :

0.1 mL

price2 :

275

size3 :

0.2 mL

price3 :

430

more info or order :

MyBioSource product webpage