product summary
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company name :
MyBioSource
product type :
antibody
product name :
CDH6 Polyclonal Antibody
catalog :
MBS9128877
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using CDH6 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
image 2 :
Immunohistochemistry of paraffin-embedded rat kidney using CDH6 antibody at dilution of 1:100 (40x lens).
image 3 :
Immunohistochemistry of paraffin-embedded human stomach using CDH6 antibody at dilution of 1:100 (40x lens).
product information
catalog number :
MBS9128877
products type :
Antibody
products full name :
CDH6 Polyclonal Antibody
products short name :
[CDH6]
products name syn :
[CAD6; KCAD]
other names :
[cadherin-6 preproprotein; Cadherin-6; cadherin-6; cadherin 6, type 2, K-cadherin (fetal kidney); Kidney cadherin; K-cadherin]
products gene name :
[CDH6]
other gene names :
[CDH6; CDH6; CAD6; KCAD; K-cadherin]
uniprot entry name :
CADH6_HUMAN
clonality :
polyclonal
isotype :
IgG
host :
unknown
reactivity :
Human, Mouse, Rat
sequence length :
790
purity :
Affinity Purification
storage stability :
Store at -20 degree C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Rabbit
other info2 :
Immunogen: Recombinant protein of human CDH6. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products description :
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
ncbi gi num :
4826673
ncbi acc num :
NP_004923.1
ncbi gb acc num :
NM_004932.3
uniprot acc num :
P55285
ncbi mol weight :
88kDa
ncbi pathways :
Adherens Junctions Interactions Pathway (1270234); Cell Junction Organization Pathway (1270232); Cell-Cell Communication Pathway (1270231); Cell-cell Junction Organization Pathway (1270233); Neural Crest Differentiation Pathway (672460)
ncbi summary :
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
uniprot summary :
CDH6: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 5p13.3. Cellular Component: plasma membrane; integral to membrane. Molecular Function: calcium ion binding. Biological Process: intercellular junction assembly and maintenance; cell adhesion; homophilic cell adhesion
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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