antibody

DAPK2 Polyclonal Antibody

MBS9128479

0.05 mL

200 USD

polyclonal

rabbit

nonconjugated

human, mouse

western blot, immunocytochemistry

Antibody

DAPK2 Polyclonal Antibody

[DAPK2]

[death-associated protein kinase 2; Death-associated protein kinase 2; death-associated protein kinase 2; death-associated protein kinase 2; DAP-kinase-related protein 1; DRP-1]

[DAPK2]

[DAPK2; DAPK2; DRP1; DRP-1; DAP kinase 2; DRP-1]

DAPK2_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

488

Affinity Purification

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20°C. Avoid freeze / thaw cycles.

Western Blot (WB), Immunofluorescence (IF)

WB 1:500 - 1:2000. IF 1:50-1:200

Immunofluorescence (IF)

Calculated MW: 42 kDa/55 kDa

Immunogen: A synthetic peptide corresponding to a sequence within amino acid 300 to the C-terminus of human DAPK2 (NP_055141.2).

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.

14670383

NP_055141.2

NM_014326.3

Q9UIK4

Apoptosis Pathway (1270262); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Caspase Activation Via Extrinsic Apoptotic Signalig Pathway (1270263); Ligand-independent Caspase Activation Via DCC Pathway (1270267); Pathways In Cancer (83105); Programmed Cell Death Pathway (1270261)

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]

DAPK2: an ubiquitously expressed protein kinase of the DAPK family. Activated by Ca(2+)/calmodulin. Contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain. Overexpression induces apoptosis. Expressed at high levels in heart, lung and skeletal muscle. Protein type: EC 2.7.11.1; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CAMK group; DAPK family. Chromosomal Location of Human Ortholog: 15q22.31. Cellular Component: cytoplasm; cytoplasmic vesicle. Molecular Function: calmodulin binding; identical protein binding; protein serine/threonine kinase activity; protein binding; calmodulin-dependent protein kinase activity; ATP binding. Biological Process: regulation of apoptosis; apoptosis; protein amino acid autophosphorylation; regulation of autophagy; protein amino acid phosphorylation; anoikis

0.05 mL

200 USD

0.1 mL

275

0.2 mL

430