Mouse Lysosome-associated membrane glycoprotein 2, LAMP2 ELISA Kit | MyBioSource MBS912810 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Lysosome-associated membrane glycoprotein 2, LAMP2 ELISA Kit

catalog :

MBS912810

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS912810

products type :

ELISA Kit

products full name :

Mouse Lysosome-associated membrane glycoprotein 2, LAMP2 ELISA Kit

products short name :

lysosomal-associated membrane protein 2

products name syn :

Mouse Lysosome-associated membrane glycoprotein 2 (LAMP2) ELISA kit; CD107b; LAMPB; LGP110; lysosome-associated membrane protein 2; lysosomal-associated membrane protein 2

other names :

lysosome-associated membrane glycoprotein 2 isoform 1; Lysosome-associated membrane glycoprotein 2; lysosome-associated membrane glycoprotein 2; lysosomal membrane glycoprotein 2; CD107 antigen-like family member B; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; CD107 antigen-like family member B; Lysosomal membrane glycoprotein type B; LGP-B; CD_antigen: CD107b

products gene name :

LAMP2

other gene names :

Lamp2; Lamp2; Mac3; LGP-B; CD107b; Lamp-2; Lamp II; Lamp-2a; Lamp-2b; Lamp-2c; Lamp-2; LAMP-2; Lysosome-associated membrane protein 2; LGP-B

uniprot entry name :

LAMP2_MOUSE

reactivity :

Mouse

sequence length :

415

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse LAMP2. No significant cross-reactivity or interference between Mouse LAMP2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 31.25 pg/ml-2000 pg/ml. Sensitivity: 7.81 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LAMP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LAMP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LAMP2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LAMP2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

63054837

ncbi acc num :

NP_001017959.1

ncbi gb acc num :

NM_001017959.2

uniprot acc num :

P17047

ncbi mol weight :

45,681 Da

ncbi pathways :

Hemostasis Pathway (575479); Lysosome Pathway (99272); Lysosome Pathway (96865); Phagosome Pathway (153914); Phagosome Pathway (153859); Platelet Activation, Signaling And Aggregation Pathway (575489); Platelet Degranulation Pathway (575501); Response To Elevated Platelet Cytosolic Ca2+ Pathway (575499); Senescence And Autophagy Pathway (198361); Tuberculosis Pathway (213781)

uniprot summary :

LAMP2: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens. Defects in LAMP2 are the cause of Danon disease (DAND); also known as glycogen storage disease type 2B (GSD2B). DAND is a lysosomal glycogen storage disease characterized by the clinical triad of cardiomyopathy, vacuolar myopathy and mental retardation. It is often associated with an accumulation of glycogen in muscle and lysosomes. Belongs to the LAMP family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Cellular Component: phagocytic vesicle membrane; membrane; lysosomal membrane; lysosome; late endosome membrane; late endosome; integral to membrane; plasma membrane; platelet dense granule membrane; endosome. Molecular Function: protein domain specific binding; enzyme binding. Biological Process: protein stabilization

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage