product summary
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company name :
MyBioSource
product type :
antibody
product name :
CEP120 Polyclonal Antibody
catalog :
MBS9127987
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9127987 image 1
Western blot analysis of extracts of various cell lines, using CEP120 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
product information
catalog number :
MBS9127987
products type :
Antibody
products full name :
CEP120 Polyclonal Antibody
products short name :
[CEP120]
products name syn :
[CEP120; CCDC100; SRTD13; centrosomal protein 120]
other names :
[centrosomal protein of 120 kDa isoform 2; Centrosomal protein of 120 kDa; centrosomal protein of 120 kDa; centrosomal protein 120kDa; Coiled-coil domain-containing protein 100]
products gene name :
[CEP120]
other gene names :
[CEP120; CEP120; SRTD13; CCDC100; CCDC100; Cep120]
uniprot entry name :
CE120_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
380
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB 1:500 - 1:2000. IHC 1:50 - 1:200
image1 heading :
Western Blot (WB)
other info1 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Calculated MW: 42 kDa/109 kDa/112kDa. Observed MW: 113 kDa
other info2 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2)
products description :
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants.
ncbi gi num :
261245061
ncbi acc num :
NP_001159698.1
ncbi gb acc num :
NM_001166226.1
uniprot acc num :
Q8N960
ncbi summary :
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
uniprot summary :
CEP120: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis. Belongs to the CEP120 family. 3 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 5q23.2. Cellular Component: centrosome; cytoplasm. Molecular Function: protein C-terminus binding. Biological Process: regulation of microtubule-based process; astral microtubule organization and biogenesis; regulation of protein localization; neurogenesis; cerebral cortex development; interkinetic nuclear migration. Disease: Short-rib Thoracic Dysplasia 13 With Or Without Polydactyly
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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