catalog number :
MBS9127788
products full name :
TP53AIP1
products short name :
TP53AIP1
other names :
p53-regulated apoptosis-inducing protein 1; p53-regulated apoptosis-inducing protein 1; p53-regulated apoptosis-inducing protein 1; tumor protein p53 regulated apoptosis inducing protein 1
products gene name :
TP53AIP1
other gene names :
TP53AIP1; TP53AIP1; P53AIP1; p53AIP1
uniprot entry name :
TPIP1_HUMAN
purity :
Affinity purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Species: Human. Immunogen: Recombinant Protein
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the
mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important
role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding
different isoforms have been described for this gene.
ncbi pathways :
DNA Damage Response Pathway (198788); P53 Pathway (138067); P53 Signaling Pathway (83055); P53 Signaling Pathway (465)
ncbi summary :
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
uniprot summary :
p53AIP1: May play an important role in mediating p53/TP53- dependent apoptosis. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Mitochondrial; Apoptosis. Chromosomal Location of Human Ortholog: 11q24. Cellular Component: mitochondrion. Biological Process: apoptosis