product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD68 Polyclonal Antibody
catalog :
MBS9127682
quantity :
0.05 mL
price :
235 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9127682 image 1
Western blot analysis of extracts of mouse spleen, using CD68 antibody. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
product information
catalog number :
MBS9127682
products type :
Antibody
products full name :
CD68 Polyclonal Antibody
products short name :
[CD68]
products name syn :
[GP110; LAMP4; SCARD1]
other names :
[Macrosialin; Macrosialin; macrosialin; CD68 antigen; macrophage antigen CD68; scavenger receptor class D, member 1; CD68 molecule; Gp110; CD_antigen: CD68]
products gene name :
[CD68]
other gene names :
[CD68; CD68; GP110; LAMP4; SCARD1]
uniprot entry name :
CD68_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
354
purity :
Affinity Purification
concentration :
1mg/ml
storage stability :
Store at -20 degree C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:1000
image1 heading :
Western Blot (WB)
other info1 :
Species: Human. Route: Synthetic Peptide
other info2 :
Immunogen: A synthetic peptide of human CD68. Calculated Molecular Weight: 37kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
ncbi gi num :
147744552
ncbi acc num :
P34810.2
uniprot acc num :
P34810
ncbi mol weight :
354
ncbi pathways :
Lysosome Pathway (99052); Lysosome Pathway (96865)
ncbi summary :
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
CD68: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. Belongs to the LAMP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13. Cellular Component: membrane; lysosomal membrane; plasma membrane; integral to membrane; endosome membrane
size1 :
0.05 mL
price1 :
235 USD
size2 :
0.1 mL
price2 :
350
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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