catalog number :
MBS9127650
products full name :
UCN2 Polyclonal Antibody
products short name :
[UCN2]
products name syn :
[SRP; UCN-II; UCNI; UR; URP]
other names :
[Urocortin-2; Urocortin-2; urocortin-2; ucn II; urocortin II; prepro-urocortin 2; urocortin-related peptide; stresscopin-related peptide; urocortin 2; Stresscopin-related peptide; Urocortin II; Ucn II; Urocortin-related peptide]
products gene name :
[UCN2]
other gene names :
[UCN2; UCN2; UR; SRP; URP; UCNI; UCN-II; SRP; URP; Ucn II]
uniprot entry name :
UCN2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity Purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:100. IF: 1:50 - 1:100
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Source: Rabbit. Immunogen: Recombinant Protein of human UCN2. Category: Primary Antibody. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
ncbi mol weight :
Calculated: 12kDa. Observed: Refer to figures
ncbi summary :
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
uniprot summary :
UCN2: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: extracellular space; extracellular region. Molecular Function: hormone binding; G-protein-coupled receptor binding; hormone activity; corticotropin-releasing hormone receptor 2 binding; receptor binding. Biological Process: cell proliferation; negative regulation of luteinizing hormone secretion; cellular response to nutrient levels; digestion; response to stress; cAMP biosynthetic process; G-protein signaling, adenylate cyclase activating pathway; negative regulation of follicle-stimulating hormone secretion