catalog number :
MBS9127629
products full name :
SKIV2L2 Polyclonal Antibody
products short name :
[MTR4]
products name syn :
[Dob1; Mtr4; fSAP118; KIAA0052]
other names :
[Superkiller viralicidic activity 2-like 2; Superkiller viralicidic activity 2-like 2; superkiller viralicidic activity 2-like 2; TRAMP-like complex helicase; ATP-dependent helicase SKIV2L2; ATP-dependent RNA helicase SKIV2L2; functional spliceosome-associated protein 118; superkiller viralicidic activity 2-like 2 (S. cerevisiae); ATP-dependent RNA helicase SKIV2L2; TRAMP-like complex helicase]
products gene name :
[SKIV2L2]
other gene names :
[SKIV2L2; SKIV2L2; Dob1; Mtr4; fSAP118; KIAA0052; KIAA0052; Mtr4]
uniprot entry name :
SK2L2_HUMAN
reactivity :
Human, Mouse
purity :
Affinity Purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IP: 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
Immunohistochemistry of paraffin-embedded human esophagus using SKIV2L2 antibody at dilution of 1:100 (40x lens).
other info1 :
Species: Human
other info2 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human SKIV2L2 (NP_056175.3). Calculated Molecular Weight: 117kDa. Observed Molecular Weight: 123kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
ncbi pathways :
RNA Degradation Pathway (117291); RNA Degradation Pathway (116127); TRAMP Complex Pathway (413459); TRAMP Complex Pathway (468399)
uniprot summary :
SKIV2L2: May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3 processing of the 7S pre-RNA to the mature 5.8S rRNA. Belongs to the helicase family. SKI2 subfamily. Protein type: Nucleolus; EC 3.6.4.13; DNA-binding; Spliceosome; Helicase. Chromosomal Location of Human Ortholog: 5q11.2. Cellular Component: nucleoplasm; nucleolus; exosome (RNase complex); nucleus. Molecular Function: protein binding; helicase activity; ATP binding. Biological Process: nuclear mRNA splicing, via spliceosome; maturation of 5.8S rRNA