SLC23A2 Polyclonal Antibody | MyBioSource MBS9127227 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

SLC23A2 Polyclonal Antibody

catalog :

MBS9127227

quantity :

0.05 mL

price :

200 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of extracts of various cell lines, using SLC23A2 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

image 2 :

Immunohistochemistry of paraffin-embedded rat brain using SLC23A2 antibody at dilution of 1:100 (40x lens).

image 3 :

Immunohistochemistry of paraffin-embedded rat kidney using SLC23A2 antibody at dilution of 1:100 (40x lens).

product information

catalog number :

MBS9127227

products type :

Antibody

products full name :

SLC23A2 Polyclonal Antibody

products short name :

[SLC23A2]

products name syn :

[NBTL1; SVCT2; YSPL2; SLC23A1]

other names :

[Solute carrier family 23 member 2; Solute carrier family 23 member 2; solute carrier family 23 member 2; hSVCT2; yolk sac permease-like molecule 2; Na(+)/L-ascorbic acid transporter 2; nucleobase transporter-like 1 protein; sodium-dependent vitamin C transporter-2; solute carrier family 23 (nucleobase transporters), member 1; solute carrier family 23 (nucleobase transporters), member 2; solute carrier family 23 (ascorbic acid transporter), member 2; Na(+)/L-ascorbic acid transporter 2; Nucleobase transporter-like 1 protein; Sodium-dependent vitamin C transporter 2; hSVCT2; Yolk sac permease-like molecule 2]

products gene name :

[SLC23A2]

other gene names :

[SLC23A2; SLC23A2; NBTL1; SVCT2; YSPL2; SLC23A1; KIAA0238; NBTL1; SLC23A1; SVCT2; YSPL2; hSVCT2]

uniprot entry name :

S23A2_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

650

purity :

Affinity Purification

storage stability :

Store at -20°C. Avoid freeze / thaw cycles.

tested application :

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

app notes :

WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. 1:10-1:100

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

Immunohistochemistry of paraffin-embedded mouse spinal cord using SLC23A2 antibody at dilution of 1:100 (40x lens).

image5 heading :

Immunohistochemistry (IHC)

image5 description :

Immunohistochemistry of paraffin-embedded mouse brain using SLC23A2 antibody at dilution of 1:100 (40x lens).

other info1 :

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

other info2 :

Immunogen: Recombinant protein of human SLC23A2. Calculated MW: 58 kDa/70kDa. Observed MW: 70kDa

products categories :

Polyclonal

products description :

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1.

ncbi gi num :

24212469

ncbi acc num :

Q9UGH3.1

uniprot acc num :

Q9UGH3

ncbi pathways :

Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway (906000); Defective BTD Causes Biotidinase Deficiency Pathway (906015); Defective CD320 Causes Methylmalonic Aciduria Pathway (906012); Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway (906001); Defective GIF Causes Intrinsic Factor Deficiency Pathway (906004); Defective HLCS Causes Multiple Carboxylase Deficiency Pathway (906014); Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway (906003); Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway (906010); Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway (906009); Defective MMACHC Causes Methylmalonic Aciduria And Homocystinuria Type CblC Pathway (906005)

ncbi summary :

uniprot summary :

SLC23A2: Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. Protein type: Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: membrane; basolateral plasma membrane; integral to plasma membrane; apical plasma membrane; cytoplasm; integral to membrane; plasma membrane; basal plasma membrane. Molecular Function: L-ascorbate:sodium symporter activity; sodium-dependent multivitamin transmembrane transporter activity; L-ascorbic acid transporter activity; nucleobase transmembrane transporter activity. Biological Process: vitamin metabolic process; molecular hydrogen transport; sodium ion transport; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; L-ascorbic acid metabolic process; nucleobase transport; response to oxidative stress; water-soluble vitamin metabolic process; L-ascorbic acid transport

size1 :

0.05 mL

price1 :

200 USD

size2 :

0.1 mL

price2 :

275

size3 :

0.2 mL

price3 :

430

more info or order :

MyBioSource product webpage