catalog number :
MBS9126862
products full name :
AZGP1 Polyclonal Antibody
products short name :
[AZGP1]
products name syn :
[ZA2G;ZAG]
other names :
[Zinc-alpha-2-glycoprotein; Zinc-alpha-2-glycoprotein; zinc-alpha-2-glycoprotein; zn-alpha-2-GP; Zn-alpha2-glycoprotein; zn-alpha-2-glycoprotein; Alpha-2-glycoprotein, zinc; alpha-2-glycoprotein 1, zinc-binding]
products gene name :
[AZGP1]
other gene names :
[AZGP1; AZGP1; ZAG; ZA2G; ZAG; ZNGP1; Zn-alpha-2-GP; Zn-alpha-2-glycoprotein]
uniprot entry name :
ZA2G_HUMAN
reactivity :
Human, Mouse
purity :
Affinity Purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
Immunohistochemistry of paraffin-embedded mouse lung using AZGP1 Antibody at dilution of 1:100 (40x lens).
other info1 :
Source: Rabbit. Species: Human
other info2 :
Immunogen: Recombinant protein of human AZGP1. Observed MW: 40kDa. Calculated MW: 34kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
Zinc-alpha-2-glycoprotein (AZGP1) is a soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).
uniprot summary :
AZGP1: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids. Belongs to the MHC class I family. Protein type: Cell adhesion; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 7q22.1. Cellular Component: extracellular space; extracellular region; plasma membrane; nucleus; MHC class I protein complex. Molecular Function: peptide antigen binding; protein transmembrane transporter activity; glycoprotein binding; antigen binding; ribonuclease activity. Biological Process: retinal homeostasis; antigen processing and presentation; negative regulation of cell proliferation; antigen processing and presentation of peptide antigen via MHC class I; positive regulation of T cell mediated cytotoxicity; immune response; detection of chemical stimulus involved in sensory perception of bitter taste; cell adhesion