product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
ELF3 Polyclonal Antibody
catalog :
MBS9126393
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using ELF3 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
image 2 :
Immunohistochemistry of paraffin-embedded rat kidney using ELF3 antibody at dilution of 1:200 (40x lens).
image 3 :
Immunofluorescence analysis of A549 cells using ELF3 antibody. Blue: DAPI for nuclear staining.
product information
catalog number :
MBS9126393
products type :
Antibody
products full name :
ELF3 Polyclonal Antibody
products short name :
[ELF3]
products name syn :
[ERT; ESX; EPR-1; ESE-1]
other names :
[ETS-related transcription factor Elf-3; ETS-related transcription factor Elf-3; ETS-related transcription factor Elf-3; ELF3; epithelial-restricted with serine box; epithelium-restricted Ets protein ESX; epithelium-specific Ets transcription factor 1; E74-like factor 3 (ets domain transcription factor); ets domain transcription factor, serine box (epithelial-specific); E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific); E74-like factor 3 (ets domain transcription factor, epithelial-specific ); E74-like factor 3; Epithelial-restricted with serine box; Epithelium-restricted Ets protein ESX; Epithelium-specific Ets transcription factor 1; ESE-1]
products gene name :
[ELF3]
other gene names :
[ELF3; ELF3; ERT; ESX; EPR-1; ESE-1; ESE-1]
uniprot entry name :
ELF3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Rat
sequence length :
371
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF 1:10-1:100
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant Fusion protein containing a sequence corresponding to amino acids 1-280 of human ELF3 (NP_004424.3). Calculated MW: 39 kDa/41kDa. Observed MW: 42kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
products categories :
Polyclonal
ncbi gi num :
74739735
ncbi acc num :
P78545.1
uniprot acc num :
P78545
ncbi pathways :
EGFR1 Signaling Pathway (198782)
uniprot summary :
ELF3: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development. Belongs to the ETS family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; Motility/polarity/chemotaxis; DNA-binding. Chromosomal Location of Human Ortholog: 1q32.2. Cellular Component: cytoplasm; nucleus. Molecular Function: protein binding; transcription coactivator activity; transcription factor activity. Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; mammary gland involution; epidermis development; extracellular matrix organization and biogenesis; blastocyst development; epithelial cell differentiation; positive regulation of transcription, DNA-dependent; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; inflammatory response
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments