product summary
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company name :
MyBioSource
product type :
antibody
product name :
TACR3
catalog :
MBS9126076
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
MyBioSource MBS9126076 image 1
Western blot analysis of extracts of various cell lines, using TACR3 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
image 2 :
MyBioSource MBS9126076 image 2
Immunohistochemistry of paraffin-embedded human stomach cancer using TACR3 antibody at dilution of 1:100 (40x lens).
product information
catalog number :
MBS9126076
products type :
Antibody
products full name :
TACR3
products short name :
[TACR3]
products name syn :
[TACR3; HH11; NK-3R; NK3R; NKR; TAC3RL; neuromedin-K receptor]
other names :
[Neuromedin-K receptor; Neuromedin-K receptor; neuromedin-K receptor; NK-3 receptor; neurokinin B receptor; neurokinin beta receptor; tachykinin receptor 3; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3]
products gene name :
[TACR3]
other gene names :
[TACR3; TACR3; NKR; HH11; NK3R; NK-3R; TAC3RL; NK3R; TAC3R; NKR; NK-3R]
uniprot entry name :
NK3R_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
465
purity :
Affinity purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
storage stability :
Store at -20°C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500-1:2000, IHC: 1:50-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 356-465 of human TACR3 (NP_001050.1).
products categories :
Polyclonal
ncbi gi num :
128364
ncbi acc num :
P29371.1
uniprot acc num :
P29371
ncbi mol weight :
52kDa
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637)
ncbi summary :
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008]
uniprot summary :
TACR3: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K substance K substance P. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR. Chromosomal Location of Human Ortholog: 4q25. Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; nucleus. Molecular Function: protein binding; tachykinin receptor activity. Biological Process: tachykinin signaling pathway; hyperosmotic salinity response; regulation of dopamine metabolic process; response to morphine; positive regulation of heart rate; response to cocaine; response to estradiol stimulus; positive regulation of blood pressure; aging. Disease: Hypogonadotropic Hypogonadism 11 With Or Without Anosmia
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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