product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
STC1
catalog :
MBS9125880
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of mouse lung, using STC1 Antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
image 2 :
Immunohistochemistry of paraffin-embedded rat kidney using STC1 antibody at dilution of 1:100 (40x lens).
image 3 :
Immunohistochemistry of paraffin-embedded human liver using STC1 antibody at dilution of 1:100 (40x lens).
product information
catalog number :
MBS9125880
products type :
Antibody
products full name :
STC1
products short name :
[STC1]
products name syn :
[STC1; STC; stanniocalcin-1]
other names :
[Stanniocalcin-1; Stanniocalcin-1; stanniocalcin-1; stanniocalcin 1]
products gene name :
[STC1]
other gene names :
[STC1; STC1; STC; STC; STC-1]
uniprot entry name :
STC1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
247
purity :
Affinity purification
form :
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB 1:500 - 1:2000. IHC 1:50 - 1:100
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
image4 heading :
Immunohistochemistry (IHC)
image4 description :
Immunohistochemistry of paraffin-embedded mouse heart using STC1 antibody at dilution of 1:100 (40x lens).
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-247 of human STC1 (NP_003146.1).
products categories :
Polyclonal
products description :
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
ncbi gi num :
1706175
ncbi acc num :
P52823.1
uniprot acc num :
P52823
ncbi mol weight :
Observed: 28kDa. Calculated: 20kDa/27kDa
ncbi summary :
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]
uniprot summary :
STC1: Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia. Belongs to the stanniocalcin family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 8p21.2. Cellular Component: extracellular space; apical plasma membrane; cytoplasm; nucleus. Molecular Function: hormone activity. Biological Process: cellular calcium ion homeostasis; ossification; negative regulation of calcium ion transport; response to vitamin D; decidualization; endothelial cell morphogenesis; negative regulation of cell migration; embryo implantation
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
related products
browse more products
questions and comments