catalog number :
MBS9125815
products full name :
EIF1AX Polyclonal Antibody
products short name :
[EIF1AX]
products name syn :
[EIF1AX; EIF1A; EIF1AP1; EIF4C; eIF-1A; eIF-4C; eukaryotic translation initiation factor 1A, X-linked]
other names :
[Eukaryotic translation initiation factor 1A, X-chromosomal; Eukaryotic translation initiation factor 1A, X-chromosomal; eukaryotic translation initiation factor 1A, X-chromosomal; eIF-1A X isoform; eukaryotic translation initiation factor 4C; Putative eukaryotic translation initiation factor 1A; eukaryotic translation initiation factor 1A, X chromosome; eukaryotic translation initiation factor 1A, X-linked; Eukaryotic translation initiation factor 4C; eIF-4C]
products gene name :
[EIF1AX]
other gene names :
[EIF1AX; EIF1AX; EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1; EIF1A; EIF4C; eIF-1A X isoform; eIF-4C]
uniprot entry name :
IF1AX_HUMAN
reactivity :
Human, Mouse, Rat
sequence positions :
[10-144]
purity :
Affinity Purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:200 - 1:2000. IHC: 1:100 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Source: Rabbit. Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 10-144 of human EIF1AX (NP_001403.1).
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA
ncbi mol weight :
Calculated: 16kDa. Observed: 16kDa
ncbi pathways :
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway (105970); Cap-dependent Translation Initiation Pathway (105967); Eukaryotic Translation Initiation Pathway (105966); Formation Of A Pool Of Free 40S Subunits Pathway (105968); Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway (105969); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (105973); Gene Expression Pathway (105937); L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway (160955); Metabolism Of Proteins Pathway (106230); RNA Transport Pathway (177876)
ncbi summary :
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]
uniprot summary :
EIF1AX: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. Belongs to the eIF-1A family. Protein type: Translation initiation; RNA-binding; Translation. Chromosomal Location of Human Ortholog: Xp22.12. Cellular Component: cytosol. Molecular Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity. Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression