catalog number :
MBS9125432
products full name :
RNPC3 Polyclonal Antibody
products short name :
[RNPC3]
products name syn :
[RNP; RBM40; SNRNP65; RNPC3; RNA-binding protein 40]
other names :
[RNA-binding protein 40; RNA-binding protein 40; RNA-binding protein 40; U11/U12-65K; U11/U12 snRNP 65K; RNA recognition protein; RNA-binding motif protein 40; U11/U12 snRNP 65 kDa protein; RNA-binding region-containing protein 3; U11/U12 small nuclear ribonucleoprotein 65 kDa protein; RNA-binding region (RNP1, RRM) containing 3; RNA-binding motif protein 40; RNA-binding region-containing protein 3; U11/U12 small nuclear ribonucleoprotein 65 kDa protein; U11/U12 snRNP 65 kDa protein; U11/U12-65K]
products gene name :
[RNPC3]
other gene names :
[RNPC3; RNPC3; RNP; RBM40; SNRNP65; KIAA1839; RBM40; RNP; U11/U12 snRNP 65 kDa protein; U11/U12-65K]
uniprot entry name :
RBM40_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity Purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:2000
image1 heading :
Western Blot (WB)
other info1 :
Species: Human. Immunogen: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human RNPC3. Calculated Molecular Weight: 58kDa
products categories :
Polyclonal
products description :
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
ncbi mol weight :
Calculated: 58 kDa. Observed: 60-75 kDa
ncbi summary :
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]
uniprot summary :
RNPC3: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3 -stem-loop of m(7)G-capped U12 snRNA. Protein type: RNA splicing. Chromosomal Location of Human Ortholog: 1p21. Cellular Component: nucleoplasm; nucleus; U12-dependent spliceosome. Molecular Function: RNA binding; nucleotide binding. Biological Process: RNA splicing; mRNA processing