product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
C9
catalog :
MBS9125401
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9125401 image 1
Western blot analysis of extracts of mouse liver, using C9 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
product information
catalog number :
MBS9125401
products type :
Antibody
products full name :
C9
products short name :
[C9]
products name syn :
[ARMD15, C9D]
other names :
[Complement component C9; Complement component C9; complement component C9; complement component 9]
products gene name :
[C9]
other gene names :
[C9; C9; C9D; ARMD15]
uniprot entry name :
CO9_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
unknown
reactivity :
Human, Mouse
sequence length :
559
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
1:500- 1:2000
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit. Immunogen: Recombinant funsion protein containing a sequence corresponding to amino acids 22-265 of human C9 (NP_001728.1). Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. Calculated MW: 63 kDa. Observed MW: 70 kDa
products categories :
Polyclonal
products description :
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
ncbi gi num :
1352108
ncbi acc num :
P02748.2
uniprot acc num :
P02748
ncbi pathways :
Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Complement Activation, Classical Pathway (198823); Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (106405); Immune System Pathway (106386); Innate Immune System Pathway (106387); Prion Diseases Pathway (101144)
ncbi summary :
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
uniprot summary :
C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family. Protein type: Extracellular matrix; Membrane protein, multi-pass; Membrane protein, integral; Apoptosis. Chromosomal Location of Human Ortholog: 5p14-p12. Cellular Component: membrane attack complex; integral to plasma membrane; cytoplasm; plasma membrane; extracellular region. Biological Process: complement activation, alternative pathway; regulation of complement activation; innate immune response; hemolysis by symbiont of host red blood cells; complement activation, classical pathway. Disease: Macular Degeneration, Age-related, 15; Complement Component 9 Deficiency
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!