antibody

RAE1 Polyclonal Antibody

MBS9125380

0.05 mL

230 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry, immunocytochemistry

Antibody

RAE1 Polyclonal Antibody

RAE1

MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1

mRNA export factor; mRNA export factor; mRNA export factor; mRNA export protein; rae1 protein homolog; RAE1 RNA export 1 homolog; migration-inducing gene 14; mRNA-binding protein, 41-kD; mRNA-associated protein MRNP 41; homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer); ribonucleic acid export 1; Rae1 protein homolog; mRNA-associated protein mrnp 41

RAE1

RAE1; RAE1; MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1; MRNP41

RAE1L_HUMAN

Polyclonal

IgG

Rabbit

Human, Mouse, Rat

368

Affinity Purification

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200

Species: Human. Immunogen: Recombinant Protein. Category: Primary Protein

Immunogen: Recombinant protein of human RAE1. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Polyclonal

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

3122666

P78406.1

P78406

40kDa

Antiviral Mechanism By IFN-stimulated Genes Pathway (530760); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Cytokine Signaling In Immune System Pathway (366171); Disease Pathway (530764); Export Of Viral Ribonucleoproteins From Nucleus Pathway (106080); Gene Expression Pathway (105937); Glucose Transport Pathway (106200); Glycogen Storage Diseases Pathway (1127581); HIV Infection Pathway (105983)

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

RAE1: Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Belongs to the WD repeat rae1 family. Protein type: Motility/polarity/chemotaxis; RNA-binding. Chromosomal Location of Human Ortholog: 20q13.31. Cellular Component: nuclear outer membrane; cytoskeleton; cytoplasm; nucleolus; nuclear pore; nuclear envelope; nucleus. Molecular Function: RNA binding; microtubule binding. Biological Process: mRNA export from nucleus; viral reproduction; hexose transport; cytokine and chemokine mediated signaling pathway; carbohydrate metabolic process; mitotic nuclear envelope disassembly; gene expression; viral transcription; pathogenesis; glucose transport; viral infectious cycle; mitotic cell cycle; transmembrane transport

0.05 mL

230 USD

0.1 mL

305

0.2 mL

460