Mouse Interleukin-23 subunit alpha, IL23A ELISA Kit | MyBioSource MBS912327 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Interleukin-23 subunit alpha, IL23A ELISA Kit

catalog :

MBS912327

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS912327

products type :

ELISA Kit

products full name :

Mouse Interleukin-23 subunit alpha, IL23A ELISA Kit

products short name :

interleukin 23, alpha subunit p19

products name syn :

Mouse Interleukin-23 subunit alpha (IL23A) ELISA kit; IL-23; IL-23A; IL23P19; MGC79388; P19; SGRF; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin 23; alpha subunit p19

other names :

interleukin-23 subunit alpha; Interleukin-23 subunit alpha; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin-23 subunit p19; interleukin 23, alpha subunit p19; Interleukin-23 subunit p19; IL-23p19

products gene name :

IL23A

other gene names :

Il23a; Il23a; p19; IL-23; IL-23 subunit alpha; IL-23-A; IL-23p19

uniprot entry name :

IL23A_MOUSE

reactivity :

Mouse

sequence length :

196

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse IL23A. No significant cross-reactivity or interference between Mouse IL23A and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 15.6 pg/ml-1000 pg/ml. Sensitivity: 3.9 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Immunity. Protein Biological Process 3: Antiviral defense

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL23A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL23A present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL23A is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL23A bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

13752579

ncbi acc num :

NP_112542.1

ncbi gb acc num :

NM_031252.2

uniprot acc num :

Q9EQ14

ncbi mol weight :

22,071 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83274); Jak-STAT Signaling Pathway (488); Pertussis Pathway (218112); Pertussis Pathway (218099); Rheumatoid Arthritis Pathway (200310); Rheumatoid Arthritis Pathway (200269); Tuberculosis Pathway (213781); Tuberculosis Pathway (213743)

uniprot summary :

IL23A: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Belongs to the IL-6 superfamily. Protein type: Cytokine; Secreted; Secreted, signal peptide. Cellular Component: extracellular space; extracellular region. Molecular Function: protein binding; cytokine activity; interleukin-23 receptor binding. Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; negative regulation of interleukin-10 production; positive regulation of T-helper 1 type immune response; positive regulation of osteoclast differentiation; positive regulation of T cell mediated cytotoxicity; positive regulation of interleukin-12 production; tissue remodeling; positive regulation of NK T cell proliferation; positive regulation of tyrosine phosphorylation of Stat4 protein; defense response to Gram-negative bacterium; positive regulation of activated T cell proliferation; positive regulation of interleukin-10 production; positive regulation of tyrosine phosphorylation of Stat3 protein; T cell proliferation; positive regulation of T cell proliferation; inflammatory response; defense response to virus; positive regulation of memory T cell differentiation; positive regulation of interleukin-17 production; positive regulation of NK T cell activation; positive regulation of natural killer cell proliferation; immune system process; positive regulation of tumor necrosis factor production; regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of interferon-gamma production; positive regulation of tyrosine phosphorylation of Stat5 protein; innate immune response; immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of defense response to virus by host

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage