product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse guanylate cyclase activator 2B (uroguanylin) , GUCA2B ELISA Kit
catalog :
MBS912299
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS912299
products type :
ELISA Kit
products full name :
Mouse guanylate cyclase activator 2B (uroguanylin) , GUCA2B ELISA Kit
products short name :
guanylate cyclase activator 2B (uroguanylin)
products name syn :
Mouse guanylate cyclase activator 2B (uroguanylin) (GUCA2B) ELISA kit; GCAP-II; UGN; guanylate cyclase activator 2B; uroguanylin; guanylate cyclase activator 2B (uroguanylin)
other names :
guanylate cyclase activator 2B preproprotein; Guanylate cyclase activator 2B; guanylate cyclase activator 2B; uroguanylin; granule cell antiserum positive 2; guanylate cyclase activator 2b (retina)
products gene name :
GUCA2B
other gene names :
Guca2b; Guca2b; Ugn; Gcap2; AV066530; UGN
uniprot entry name :
GUC2B_MOUSE
reactivity :
Mouse
sequence length :
106
specificity :
This assay has high sensitivity and excellent specificity for detection of mouse GUCA2B. No significant cross-reactivity or interference between mouse GUCA2B and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 7.8 pg/ml -500 pg/ml. Sensitivity: 1.95 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GUCA2B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GUCA2B present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GUCA2B is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GUCA2B bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
160298221
ncbi acc num :
NP_032217.2
ncbi gb acc num :
NM_008191.2
uniprot acc num :
O09051
ncbi mol weight :
11,628 Da
ncbi pathways :
Myometrial Relaxation And Contraction Pathways (198333)
ncbi summary :
This gene encodes a member of the guanylin family and preproprotein that is proteolytically processed to generate a mature protein product. The mature protein product, known as uroguanylin, is an endogenous ligand for the guanylate cyclase-C receptor and may regulate salt and water homeostasis in the intestine and kidneys. Homozygous knockout mice for this gene exhibit impaired sodium chloride excretion and elevated arterial pressure. This gene is present in a gene cluster with a related guanylin family member on chromosome 4. [provided by RefSeq, Sep 2015]
uniprot summary :
GUCA2B: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. Belongs to the guanylin family. Protein type: Secreted; Secreted, signal peptide. Cellular Component: photoreceptor outer segment; extracellular region. Molecular Function: guanylate cyclase activator activity. Biological Process: cGMP biosynthetic process; regulation of cyclic nucleotide biosynthetic process; negative regulation of blood pressure; excretion; body fluid secretion
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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