product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAMTS5 ELISA Kit
catalog :
MBS911846
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS911846
products type :
ELISA Kit
products full name :
Human A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAMTS5 ELISA Kit
products short name :
ADAM metallopeptidase with thrombospondin type 1 motif, 5
products name syn :
Human A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5) ELISA kit; ADAMTS11; ADMP-2; FLJ36738; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 5 (aggrecanase-2) ; aggrecanase-2; ADAM metallopeptidase with thrombospondin type 1 motif; 5
other names :
A disintegrin and metalloproteinase with thrombospondin motifs 5; A disintegrin and metalloproteinase with thrombospondin motifs 5; A disintegrin and metalloproteinase with thrombospondin motifs 5; ADMP-2; ADAM-TS5; ADAMTS-5; ADAM-TS 5; aggrecanase-2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADMP-2; Aggrecanase-2
products gene name :
ADAMTS5
other gene names :
ADAMTS5; ADAMTS5; ADAM-TS 5; ADAM-TS5; ADAMTS-5
uniprot entry name :
ATS5_BOVIN
reactivity :
Human
sequence length :
207
specificity :
This assay has high sensitivity and excellent specificity for detection of Human ADAMTS5. No significant cross-reactivity or interference between Human ADAMTS5 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 15.6 ng/ml-1000 ng/ml. Sensitivity: 3.9 ng/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAMTS5 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAMTS5 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAMTS5 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAMTS5 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
11131363
ncbi acc num :
Q9TT92.1
uniprot acc num :
Q9TT92
ncbi mol weight :
22,576 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
Function: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period. Catalytic activity: Cleaves aggrecan at the 392-Glu- -Ala-393 site. Cofactor: Binds 1 zinc ion per subunit
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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