Mouse Mannan-binding lectin serine protease 2, MASP2 ELISA Kit | MyBioSource MBS911817 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Mannan-binding lectin serine protease 2, MASP2 ELISA Kit

catalog :

MBS911817

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS911817

products type :

ELISA Kit

products full name :

Mouse Mannan-binding lectin serine protease 2, MASP2 ELISA Kit

products short name :

[mannan-binding lectin serine peptidase 2]

products name syn :

[Mouse Mannan-binding lectin serine protease 2 (MASP2) ELISA kit; MAP19; MASP-2; sMAP; MBL-associated plasma protein of 19 kD; MBL-associated serine protease 2; mannan-binding lectin serine protease 2; small MBL-associated protein; mannan-binding lectin serine peptidase 2]

other names :

[mannan-binding lectin serine protease 2 isoform 1; Mannan-binding lectin serine protease 2; mannan-binding lectin serine protease 2; MBL-associated serine protease 2; mannose-binding protein-associated serine protease 2; mannan-binding lectin serine peptidase 2; MBL-associated serine protease 2; Mannose-binding protein-associated serine protease 2; MASP-2]

products gene name :

[MASP2]

other gene names :

[Masp2; Masp2; MAp19; MASP-2; MASP-2]

uniprot entry name :

MASP2_MOUSE

reactivity :

Mouse

sequence length :

685

specificity :

This assay has high sensitivity and excellent specificity for detection of mouse MASP2. No significant cross-reactivity or interference between mouse MASP2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, plasma and tissue homogenates. Detection Range: 125 pg/ml - 8000 pg/mL. Sensitivity: <31.2 pg/mL

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with MASP2. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for MASP2. The competitive inhibition reaction is launched between with pre-coated MASP2 and MASP2 in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of MASP2 in the samples. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

54112422

ncbi acc num :

NP_001003893.1

ncbi gb acc num :

NM_001003893.2

uniprot acc num :

Q91WP0

ncbi mol weight :

75,517 Da

ncbi pathways :

Complement And Coagulation Cascades Pathway (198335); Complement And Coagulation Cascades Pathway (83270); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (575148); Creation Of C4 And C2 Activators Pathway (575150); Immune System Pathway (575095); Initial Triggering Of Complement Pathway (575149); Innate Immune System Pathway (575115); Lectin Pathway Of Complement Activation (575151); Staphylococcus Aureus Infection Pathway (172855)

uniprot summary :

MASP2: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. Defects in MASP2 are the cause of MASP2 deficiency (MASPD). MASPD is a disorder that results in autoimmune manifestations, recurrent severe infections, and chronic inflammatory disease. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.21.104. Cellular Component: extracellular region. Molecular Function: peptidase activity; protein binding; hydrolase activity; serine-type peptidase activity; metal ion binding; serine-type endopeptidase activity; complement component C4b binding; calcium ion binding; calcium-dependent protein binding; catalytic activity. Biological Process: immune system process; innate immune response; complement activation, lectin pathway; proteolysis; complement activation, classical pathway; complement activation

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

495

size3 :

96-Strip-Wells

price3 :

710

size4 :

5x96-Strip-Wells

price4 :

2705

size5 :

10x96-Strip-Wells

price5 :

5145

more info or order :

MyBioSource product webpage