Mouse Mannan-binding lectin serine protease 1, MASP1 ELISA Kit | MyBioSource MBS911651 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Mannan-binding lectin serine protease 1, MASP1 ELISA Kit

catalog :

MBS911651

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS911651

products type :

ELISA Kit

products full name :

Mouse Mannan-binding lectin serine protease 1, MASP1 ELISA Kit

products short name :

mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

products name syn :

Mouse Mannan-binding lectin serine protease 1 (MASP1) ELISA kit; CRARF; CRARF1; DKFZp686I01199; FLJ26383; MASP; MGC126283; MGC126284; PRSS5; RaRF; Ra-reactive factor serine protease p100; manan-binding lectin serine protease-1; mannan-binding lectin serine protease; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

other names :

mannan-binding lectin serine protease 1; Mannan-binding lectin serine protease 1; mannan-binding lectin serine protease 1; raRF; MASP-1; serine protease 5; complement factor MASP-3; ra-reactive factor serine protease p100; mannose-binding protein-associated serine protease; mannose-binding lectin-associated serine protease 1; complement-activating component of Ra-reactive factor; mannan-binding lectin serine peptidase 1; Complement factor MASP-3; Complement-activating component of Ra-reactive factor; Mannose-binding lectin-associated serine protease 1; MASP-1; Mannose-binding protein-associated serine protease; Ra-reactive factor serine protease p100; RaRF; Serine protease 5Cleaved into the following 2 chains:Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain

products gene name :

MASP1

other gene names :

Masp1; Masp1; CCPII; Crarf; Masp1/3; AW048060; Crarf; Masp3; MASP-1; RaRF

uniprot entry name :

MASP1_MOUSE

reactivity :

Mouse

sequence length :

704

specificity :

This assay has high sensitivity and excellent specificity for detection of Mouse MASP1. No significant cross-reactivity or interference between Mouse MASP1 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Complement. Protein Biological Process 3: Complement activation lectin pathway

ncbi gi num :

148226524

ncbi acc num :

NP_032581.2

ncbi gb acc num :

NM_008555.2

uniprot acc num :

P98064

ncbi mol weight :

79,968 Da

ncbi pathways :

Complement Activation, Classical Pathway (198379); Complement And Coagulation Cascades Pathway (198335); Complement And Coagulation Cascades Pathway (83270); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (575148); Creation Of C4 And C2 Activators Pathway (575150); Immune System Pathway (575095); Initial Triggering Of Complement Pathway (575149); Innate Immune System Pathway (575115); Lectin Pathway Of Complement Activation (575151)

uniprot summary :

MASP1: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Defects in MASP1 are the cause of 3MC syndrome type 1 (3MC1). 3MC1 is a disorder characterized by facial dysmorphism that includes hypertelorism, blepharophimosis, blepharoptosis and highly arched eyebrows, cleft lip and/or palate, craniosynostosis, learning disability and genital, limb and vesicorenal anomalies. The term 3MC syndrome includes Carnevale, Mingarelli, Malpuech, and Michels syndromes. Belongs to the peptidase S1 family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.21.-; Secreted, signal peptide; Protease; Secreted. Cellular Component: extracellular space; extracellular region. Molecular Function: peptidase activity; protein homodimerization activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; metal ion binding; calcium ion binding; calcium-dependent protein binding; catalytic activity. Biological Process: immune system process; innate immune response; complement activation, lectin pathway; proteolysis; complement activation

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage