Human C-X-C motif chemokine 3, CXCL3 ELISA Kit | MyBioSource MBS910472 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human C-X-C motif chemokine 3, CXCL3 ELISA Kit

catalog :

MBS910472

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS910472

products type :

ELISA Kit

products full name :

Human C-X-C motif chemokine 3, CXCL3 ELISA Kit

products short name :

chemokine (C-X-C motif) ligand 3

products name syn :

Human C-X-C motif chemokine 3 (CXCL3) ELISA kit; CINC-2b; GRO3; GROg; MIP-2b; MIP2B; SCYB3; GRO3 oncogene; MGSA gamma; melanoma growth stimulatory activity gamma; chemokine (C-X-C motif) ligand 3

other names :

C-X-C motif chemokine 3; C-X-C motif chemokine 3; C-X-C motif chemokine 3; GRO-gamma; MIP2-beta; MGSA gamma; GRO3 oncogene; GRO-gamma(1-73); growth-regulated protein gamma; macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; chemokine (C-X-C motif) ligand 3; GRO-gamma(1-73); Growth-regulated protein gamma; GRO-gamma; Macrophage inflammatory protein 2-beta; MIP2-beta

products gene name :

CXCL3

other gene names :

CXCL3; CXCL3; GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b; GRO3; GROG; SCYB3; GRO-gamma; MIP2-beta

uniprot entry name :

CXCL3_HUMAN

reactivity :

Human

sequence length :

107

specificity :

This assay has high sensitivity and excellent specificity for detection of human CXCL3. No significant cross-reactivity or interference between human CXCL3 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 9.37 pg/ml -600 pg/ml. Sensitivity: The minimum detectable dose of human CXCL3 is typically less than 2.34 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CXCL3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CXCL3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CXCL3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CXCL3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

54144650

ncbi acc num :

NP_002081.2

ncbi gb acc num :

NM_002090.2

uniprot acc num :

P19876

ncbi mol weight :

11,342 Da

ncbi pathways :

Chemokine Receptors Bind Chemokines Pathway (106359); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Legionellosis Pathway (469200)

ncbi summary :

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]

uniprot summary :

CXCL3: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Belongs to the intercrine alpha (chemokine CxC) family. Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q21. Cellular Component: extracellular space; extracellular region. Molecular Function: chemokine activity; CXCR chemokine receptor binding. Biological Process: G-protein coupled receptor protein signaling pathway; neutrophil chemotaxis; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; inflammatory response; regulation of cell proliferation

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage