Human parathyroid hormone 1-34, PTH 1-34antibody ELISA Kit | MyBioSource MBS910387 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human parathyroid hormone 1-34, PTH 1-34antibody ELISA Kit

catalog :

MBS910387

quantity :

48-Strip-Wells

price :

565 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS910387

products type :

ELISA Kit

products full name :

Human parathyroid hormone 1-34, PTH 1-34antibody ELISA Kit

products short name :

parathyroid hormone 1-34 (PTH 1-34) antibody

products name syn :

Human parathyroid hormone 1-34 (PTH 1-34) antibody ELISA kit; parathyroid hormone 1-34 (PTH 1-34) antibody

other names :

Parathyroid hormone; Parathyroid hormone; parathyroid hormone; parathyrin; prepro-PTH; parathormone; parathyroid hormone 1; preproparathyroid hormone; parathyroid hormone; Parathormone; Parathyrin

other gene names :

PTH; PTH; PTH1; PTH

uniprot entry name :

PTHY_HUMAN

reactivity :

Human

sequence length :

115

specificity :

This assay has high sensitivity and excellent specificity for detection of human PTH 1-34 antibody. No significant cross-reactivity or interference between human PTH 1-34 antibody and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay This assay employs the qualitative enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with antigen. Samples are pipetted into the wells with anti-human immunoglobulin conjugated Horseradish Peroxidase (HRP). Any antibodies specific for the antigen present will bind to the pre-coated antigen. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of human PTH 1-34 antibody bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

131547

ncbi acc num :

P01270.1

uniprot acc num :

P01270

ncbi mol weight :

12,861 Da

ncbi pathways :

Class B/2 (Secretin Family Receptors) Pathway (106378); Endochondral Ossification Pathway (198812); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Osteoblast Signaling Pathway (198842); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); Vitamin D Synthesis Pathway (198764)

ncbi summary :

The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008]

uniprot summary :

PTH: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2- deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Belongs to the parathyroid hormone family. Protein type: Secreted; Hormone; Apoptosis; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11p15.3-p15.1. Cellular Component: extracellular space; extracellular region. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; type 1 parathyroid hormone receptor binding; parathyroid hormone receptor binding; peptide hormone receptor binding; hormone activity. Biological Process: response to drug; transcription from RNA polymerase II promoter; positive regulation of signal transduction; induction of apoptosis by hormones; positive regulation of glycogen biosynthetic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of bone mineralization; G-protein signaling, adenylate cyclase activating pathway; Rho protein signal transduction; cellular calcium ion homeostasis; positive regulation of glucose import; G-protein coupled receptor protein signaling pathway; response to ethanol; response to cadmium ion; response to vitamin D; cAMP metabolic process; cell-cell signaling; regulation of gene expression; response to lead ion; positive regulation of cAMP biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; skeletal development; bone resorption. Disease: Hypoparathyroidism, Familial Isolated

size1 :

48-Strip-Wells

price1 :

565 USD

size2 :

96-Strip-Wells

price2 :

810

size3 :

5x96-Strip-Wells

price3 :

2750

size4 :

10x96-Strip-Wells

price4 :

5150

more info or order :

MyBioSource product webpage