catalog number :
MBS909422
products type :
ELISA Kit
products full name :
Rat 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-1, PLCG1 ELISA Kit
products short name :
phospholipase C, gamma 1
products name syn :
Rat 1-phosphatidylinositol-4; 5-bisphosphate phosphodiesterase gamma-1 (PLCG1) ELISA kit; NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1; 1-phosphatidyl-D-myo-inositol-4; 5-bisphosphate; 1-phosphatidylinositol-4; 5-bisphosphate phosphodiesterase gamma 1; OTTHUMP00000178982; PLC-gamma-1; inositoltrisp; phospholipase C; gamma 1
other names :
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; PLC-II; PLC-148; PLC-gamma-1; phospholipase C-gamma-1; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; phospholipase C, gamma 1; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-gamma-1; PLC-gamma-1
products gene name :
PLCG1
other gene names :
Plcg1; Plcg1; PPLCA; PLC-gamma-1
uniprot entry name :
PLCG1_RAT
specificity :
This assay has high sensitivity and excellent specificity for detection of Rat PLCG1. No significant cross-reactivity or interference between Rat PLCG1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm
other info2 :
Sample Volume: 50-100ul. Protein Biological Process 1: Biosynthesis/Metabolism. Protein Biological Process 2: Lipogenesis and lipometabolism. Protein Biological Process 3: Lipid degradation
ncbi acc num :
NP_037319.1
ncbi gb acc num :
NM_013187.1
ncbi mol weight :
148,548 Da
ncbi pathways :
Adaptive Immune System Pathway 573825!!Axon Guidance Pathway 574273!!B Cell Receptor Signaling Pathway 198486!!Calcium Signaling Pathway 83442!!Calcium Signaling Pathway 459!!DAG And IP3 Signaling Pathway 573632!!Developmental Biology Pathway 574272!!Disease Pathway 573628!!Downstream Signal Transduction Pathway 574194!!Downstream Signaling Of Activated FGFR Pathway 574131
ncbi summary :
mediates intracellular agonist-induced Ca2+ entry (ACE); serves as a guanine nucleotide exchange factor for the nuclear GTPase PIKE [RGD, Feb 2006]
uniprot summary :
Function: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration . Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol. Cofactor: Calcium. Enzyme regulation: Activated by phosphorylation on tyrosine residues