catalog number :
MBS907306
products type :
ELISA Kit
products full name :
Human Regenerating islet-derived protein 3-gamma, REG3G ELISA Kit
products short name :
regenerating islet-derived 3 gamma
products name syn :
Human Regenerating islet-derived protein 3-gamma (REG3G) ELISA kit; MGC118998; MGC118999; MGC119001; PAP1B; PAPIB; REG-III; UNQ429; LPPM429; PAP IB protein; regenerating gene III; regenerating islet-derived 3 gamma
other names :
regenerating islet-derived protein 3-gamma isoform 1; Regenerating islet-derived protein 3-gamma; Pancreatitis-associated protein 1B; PAP-1B; Pancreatitis-associated protein IB; PAP IB; Regenerating islet-derived protein III-gamma; REG III; Reg III-gamma
products gene name :
REG3G
other gene names :
REG3G; PAP1B; UNQ429/PRO162; REG-3-gamma; PAP-1B; PAP IB; REG III; Reg III-gamma
uniprot entry name :
REG3G_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of Human REG3G. No significant cross-reactivity or interference between Human REG3G and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 3.12 ng/ml-200 ng/ml. Sensitivity: 0.78 ng/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Immunity. Protein Biological Process 3: Acute phase
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for REG3G has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any REG3G present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for REG3G is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of REG3G bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001008388.1
ncbi gb acc num :
NM_001008387.2
ncbi mol weight :
19,330 Da
ncbi summary :
This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antimicrobial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Nov 2014]
uniprot summary :
REG3G: Might be a stress protein involved in the control of bacterial proliferation. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 2p12. Cellular Component: cytoplasm; extracellular region. Molecular Function: carbohydrate binding. Biological Process: MyD88-dependent toll-like receptor signaling pathway; defense response to Gram-positive bacterium; negative regulation of keratinocyte differentiation; acute-phase response
size4 :
10x96-Strip-Wells