product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Interleukin-18 receptor 1, IL18R1 ELISA Kit
catalog :
MBS906776
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS906776
products type :
ELISA Kit
products full name :
Human Interleukin-18 receptor 1, IL18R1 ELISA Kit
products short name :
interleukin 18 receptor 1
products name syn :
Human Interleukin-18 receptor 1 (IL18R1) ELISA kit; CD218a; CDw218a; IL-1Rrp; IL18RA; IL1RRP; IL1 receptor-related protein; OTTHUMP00000161340; OTTHUMP00000203113; cytokine receptor; interleukin 18 receptor 1
other names :
interleukin-18 receptor 1 isoform 2; Interleukin-18 receptor 1; interleukin-18 receptor 1; IL-18R1; IL1R-rp; IL-18R-1; cytokine receptor; IL1 receptor-related protein; CD218 antigen-like family member A; interleukin 18 receptor 1; CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein; IL-1Rrp; IL1R-rp; CD_antigen: CD218a
products gene name :
IL18R1
other gene names :
IL18R1; IL18R1; CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp; IL1RRP; IL-18R-1; IL-18R1; IL-1Rrp; IL1R-rp
uniprot entry name :
IL18R_HUMAN
reactivity :
Human
sequence length :
385
specificity :
This assay has high sensitivity and excellent specificity for detection of Human IL18R1. No significant cross-reactivity or interference between Human IL18R1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 0.156 ng/ml-10 ng/ml. Sensitivity: 0.039 ng/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL18R1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL18R1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL18R1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL18R1 bound in the initial step. The color development is stopped and the intensity of the color is measured
ncbi gi num :
538918830
ncbi acc num :
NP_001269328.1
ncbi gb acc num :
NM_001282399.1
uniprot acc num :
Q13478
ncbi mol weight :
62,304 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); IL12 Signaling Mediated By STAT4 Pathway (137936); IL12-mediated Signaling Events Pathway (137922); IL23-mediated Signaling Events Pathway (138000)
ncbi summary :
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
uniprot summary :
IL18R1: Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q12. Cellular Component: plasma membrane; integral to membrane. Molecular Function: protein binding; receptor activity; interleukin-1 receptor activity; interleukin-18 receptor activity. Biological Process: positive regulation of interferon-gamma production; T-helper 1 cell differentiation; natural killer cell activation; immune response; positive regulation of NF-kappaB import into nucleus; signal transduction
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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