Human Hyaluronan-binding protein 2, HABP2 ELISA Kit | MyBioSource MBS906566 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Hyaluronan-binding protein 2, HABP2 ELISA Kit

catalog :

MBS906566

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS906566

products type :

ELISA Kit

products full name :

Human Hyaluronan-binding protein 2, HABP2 ELISA Kit

products short name :

hyaluronan binding protein 2

products name syn :

Human Hyaluronan-binding protein 2 (HABP2) ELISA kit; FSAP; HABP; HGFAL; PHBP; factor VII activating protein; hepatocyte growth factor activator-like protein; hyaluronic acid binding protein 2; plasma hyaluronan binding protein; hyaluronan binding protein 2

other names :

hyaluronan-binding protein 2 isoform 2; Hyaluronan-binding protein 2; hyaluronan-binding protein 2; factor VII activating protein; factor VII-activating protease; factor seven-activating protease; hyaluronic acid binding protein 2; plasma hyaluronan binding protein; plasma hyaluronan-binding protein; hepatocyte growth factor activator-like protein; hyaluronan binding protein 2; Factor VII-activating protease; Factor seven-activating protease; FSAP; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding proteinCleaved into the following 4 chains:Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form

products gene name :

HABP2

other gene names :

HABP2; HABP2; FSAP; HABP; PHBP; HGFAL; HGFAL; PHBP; FSAP

uniprot entry name :

HABP2_HUMAN

reactivity :

Human

sequence length :

534

specificity :

This assay has high sensitivity and excellent specificity for detection of Human HABP2. No significant cross-reactivity or interference between Human HABP2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.312 ng/ml-20 ng/ml. Sensitivity: 0.078 ng/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for HABP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any HABP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for HABP2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of HABP2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

295054188

ncbi acc num :

NP_001171131.1

ncbi gb acc num :

NM_001177660.1

uniprot acc num :

Q14520

ncbi mol weight :

62,672 Da

ncbi summary :

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

uniprot summary :

HABP2: Cleaves the alpha-chain at multiple sites and the beta- chain between Lys-53 and Lys-54 but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro- urokinase) to the active two chain form. Activates coagulation factor VII. Belongs to the peptidase S1 family. Protein type: Protease; Secreted, signal peptide; Cell adhesion; Motility/polarity/chemotaxis; Secreted; EC 3.4.21.-. Chromosomal Location of Human Ortholog: 10q25.3. Cellular Component: extracellular space; extracellular region. Molecular Function: glycosaminoglycan binding; serine-type endopeptidase activity. Biological Process: proteolysis; cell adhesion. Disease: Thrombophilia Due To Thrombin Defect; Thyroid Cancer, Nonmedullary, 5

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage