Human Interferon alpha/beta receptor 2, IFNAR2 ELISA Kit | MyBioSource MBS906140 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Interferon alpha/beta receptor 2, IFNAR2 ELISA Kit

catalog :

MBS906140

quantity :

96 Strip Wells

price :

760 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS906140

products type :

ELISA Kit

products full name :

Human Interferon alpha/beta receptor 2, IFNAR2 ELISA Kit

products short name :

interferon (alpha, beta and omega) receptor 2

products name syn :

Human Interferon alpha/beta receptor 2 (IFNAR2) ELISA kit; IFN-R; IFN-alpha-REC; IFNABR; IFNARB; OTTHUMP00000067674; human interferon alpha/beta receptor; interferon alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; type I interferon receptor; interferon (alpha; beta and omega) receptor 2

other names :

interferon alpha/beta receptor 2 isoform b; Interferon alpha/beta receptor 2; interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha/beta receptor 2; type I interferon receptor 2; interferon alpha binding protein; human interferon alpha/beta receptor; interferon-alpha/beta receptor beta chain; interferon (alpha, beta and omega) receptor 2; Interferon alpha binding protein; Type I interferon receptor 2

products gene name :

IFNAR2

other gene names :

IFNAR2; IFNAR2; IFN-R; IFNABR; IFNARB; IFN-alpha-REC; IFNABR; IFNARB; IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2

uniprot entry name :

INAR2_HUMAN

reactivity :

Human

sequence length :

331

specificity :

This assay has high sensitivity and excellent specificity for detection of Human IFNAR2. No significant cross-reactivity or interference between Human IFNAR2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Sample Type: serum, plasma, tissue homogenates, cell culture supernates. Detection Range: 0.156 ng/ml-10 ng/ml. Detection Wavelength: 450 nm. Sensitivity: 0.039 ng/ml

other info2 :

Sample Volume: 50-100ul

products description :

For Samples For the quantitative determination of human interferon alpha/beta receptor 2 (IFNAR2) concentrations in serum, plasma, cell culture supernates, tissue homogenates. PRINCIPLE OF THE ASSAY This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IFNAR2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IFNAR2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IFNAR2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IFNAR2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

19923129

ncbi acc num :

NP_000865.2

ncbi gb acc num :

NM_000874.4

uniprot acc num :

P48551

ncbi mol weight :

57,759 Da

ncbi pathways :

Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018!!Hepatitis C Pathway 173973!!Hepatitis C Pathway 173907!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865!!Immune System Pathway 106386!!Influenza A Pathway 217173

ncbi summary :

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

Function: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.5 PublicationsManual assertion based on experiment in:Ref.1

size :

96 Strip Wells

price :

760 USD

more info or order :

MyBioSource product webpage