catalog number :
MBS905546
products type :
ELISA Kit
products full name :
Human Tensin-1, TNS1 ELISA Kit
products short name :
tensin 1
products name syn :
Human Tensin-1 (TNS1) ELISA kit; MSTP091; DKFZp586K0617; MGC88584; MST091; MST122; MST127; MSTP122; MSTP127; MXRA6; TNS; Matrix-remodelling-associated protein 6; matrix-remodelling associated 6; tensin; tensin 1
other names :
tensin-1; Tensin-1; tensin-1; matrix-remodelling associated 6; Matrix-remodelling-associated protein 6; protein phosphatase 1, regulatory subunit 155; tensin 1
products gene name :
TNS1
other gene names :
TNS1; TNS1; TNS; MXRA6; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; PPP1R155; TNS
uniprot entry name :
TENS1_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human TNS1. No significant cross-reactivity or interference between human TNS1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates, cell lysates. Assay Type: Sandwich. Detection Range: 23.5 pg/ml -1500 pg/ml. Sensitivity: 5.8 pg /ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TNS1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TNS1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNS1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNS1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_072174.3
ncbi gb acc num :
NM_022648.4
ncbi mol weight :
185,701 Da
ncbi pathways :
Integrin-mediated Cell Adhesion Pathway (198816)
ncbi summary :
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
tensin 1: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 2q35-q36. Cellular Component: focal adhesion; cell surface; cytoskeleton; cytoplasm. Molecular Function: protein binding; actin binding. Biological Process: cell-substrate junction assembly
size4 :
10x96-Strip-Wells