Mouse ADAM metallopeptidase with thrombospondin type 1 motif, 13, ADAMTS13 ELISA Kit | MyBioSource MBS901541 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse ADAM metallopeptidase with thrombospondin type 1 motif, 13, ADAMTS13 ELISA Kit

catalog :

MBS901541

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS901541

products type :

ELISA Kit

products full name :

Mouse ADAM metallopeptidase with thrombospondin type 1 motif, 13, ADAMTS13 ELISA Kit

products short name :

ADAM metallopeptidase with thrombospondin type 1 motif, 13

products name syn :

Mouse ADAM metallopeptidase with thrombospondin type 1 motif; 13 (ADAMTS13) ELISA kit; C9orf8; DKFZp434C2322; FLJ42993; MGC118899; MGC118900; TTP; VWFCP; vWF-CP; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 13; vWF-cleaving protease; von Wil; ADAM metallopeptidase with thrombospondin type 1 motif; 13

other names :

A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform 1; A disintegrin and metalloproteinase with thrombospondin motifs 13; A disintegrin and metalloproteinase with thrombospondin motifs 13; vWF-cleaving protease; von Willebrand factor-cleaving protease; vWF-CP mRNA for von Willebrand factor-cleaving; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13; von Willebrand factor-cleaving protease; vWF-CP; vWF-cleaving protease

products gene name :

ADAMTS13

other gene names :

Adamts13; Adamts13; Gm710; vWF-CP; ADAM-TS13; ADAMTS-13; Gm710; ADAM-TS 13; ADAM-TS13; ADAMTS-13; vWF-CP; vWF-cleaving protease

uniprot entry name :

ATS13_MOUSE

reactivity :

Mouse

sequence length :

1426

specificity :

This assay has high sensitivity and excellent specificity for detection of mouse ADAMTS13. No significant cross-reactivity or interference between mouse ADAMTS13 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 78 pg/ml -5000 pg/ml. Sensitivity: The minimum detectable dose of mouse ADAMTS13 is typically less than 19.5 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAMTS13 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAMTS13 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAMTS13 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAMTS13 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

47604978

ncbi acc num :

NP_001001322.1

ncbi gb acc num :

NM_001001322.2

uniprot acc num :

Q769J6

ncbi mol weight :

155,357 Da

uniprot summary :

ADAMTS13: Cleaves the vWF multimers in plasma into smaller forms. Defects in ADAMTS13 are the cause of thrombotic thrombocytopenic purpura congenital (TTP); also known as Upshaw-Schulman syndrome (USS). A hematologic disease characterized by hemolytic anemia with fragmentation of erythrocytes, thrombocytopenia, diffuse and non-focal neurologic findings, decreased renal function and fever. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.24.87; Motility/polarity/chemotaxis; Protease; Calcium-binding; Secreted; Secreted, signal peptide; Extracellular matrix. Cellular Component: proteinaceous extracellular matrix; extracellular space; extracellular region. Molecular Function: peptidase activity; zinc ion binding; hydrolase activity; metallopeptidase activity; metal ion binding; metalloendopeptidase activity; endopeptidase activity. Biological Process: hemostasis; peptide catabolic process; blood coagulation; proteolysis

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage