Human SLAM family member 5, CD84 ELISA Kit | MyBioSource MBS900551 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human SLAM family member 5, CD84 ELISA Kit

catalog :

MBS900551

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS900551

products type :

ELISA Kit

products full name :

Human SLAM family member 5, CD84 ELISA Kit

products short name :

CD84 molecule

products name syn :

Human SLAM family member 5 (CD84) ELISA kit; DKFZp781E2378; LY9B; SLAMF5; hCD84; mCD84; CD84 antigen (leukocyte antigen) ; leucocyte differentiation antigen CD84; leukocyte antigen CD84; leukocyte differentiation antigen CD84; CD84 molecule

other names :

SLAM family member 5 isoform 1; SLAM family member 5; SLAM family member 5; hly9-beta; leukocyte antigen CD84; cell surface antigen MAX.3; CD84 antigen (leukocyte antigen); leucocyte differentiation antigen CD84; leukocyte differentiation antigen CD84; signaling lymphocytic activation molecule 5; CD84 molecule; Cell surface antigen MAX.3; Hly9-beta; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; CD_antigen: CD84

products gene name :

CD84

other gene names :

CD84; CD84; LY9B; hCD84; mCD84; SLAMF5; SLAMF5

uniprot entry name :

SLAF5_HUMAN

reactivity :

Human

sequence length :

345

specificity :

This assay has high sensitivity and excellent specificity for detection of human CD84. No significant cross-reactivity or interference between human CD84 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.312 ng/ml -20 ng/ml. Sensitivity: The minimum detectable dose of human CD84 is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

. Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CD84 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CD84 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CD84 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CD84 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

296434285

ncbi acc num :

NP_001171808.1

ncbi gb acc num :

NM_001184879.1

uniprot acc num :

Q9UIB8

ncbi mol weight :

38,782 Da

ncbi pathways :

Cell Surface Interactions At The Vascular Wall Pathway (106062); Hemostasis Pathway (106028)

ncbi summary :

This gene encodes a membrane glycoprotein that is a member of the signaling lymphocyte activation molecule (SLAM) family. This family forms a subset of the larger CD2 cell-surface receptor Ig superfamily. The encoded protein is a homophilic adhesion molecule that is expressed in numerous immune cells types and is involved in regulating receptor-mediated signaling in those cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

uniprot summary :

CD84: Plays a role as adhesion receptor functioning by homophilic interactions and by clustering. Recruits SH2 domain- containing proteins SH2D1A/SAP. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway. May serve as a marker for hematopoietic progenitor cells. 7 isoforms of the human protein are produced by alternative splicing. Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell surface; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 1q24. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding; receptor activity. Biological Process: defense response; homophilic cell adhesion; blood coagulation; leukocyte migration

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage