catalog number :
MBS859919
products full name :
Centaurin-beta1 (Phospho-Ser554) Antibody
products short name :
[Centaurin-beta1]
products name syn :
[ACAP1; CEB1; CENB1; CENTB1; KIAA0050; Similar to centaurin, beta 1]
other names :
[arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1; Centaurin-beta-1; Cnt-b1]
products gene name :
[Cnt-b1]
other gene names :
[ACAP1; ACAP1; CENTB1; CENTB1; KIAA0050; Cnt-b1]
specificity :
Centaurin- 1 (Phospho-Ser554) antibody detects endogenous levels of Centaurin- 1 only when phosphorylated at serine 554.
purity :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
form :
In phosphate buffered saline (without Mg 2+ and Ca 2+ ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year.
tested application :
Immunohistochemistry (IHC), ELISA (EIA)
app notes :
IHC: 1:50~1:100. ELISA: 1:1000
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Centaurin- 1 around the phosphorylation site of serine 554 (P-G-S P -L-R).
other info2 :
All Sites: Human: Ser554
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products references :
Nomura N., DNA Res. 1:223-229(1994). Kalnine N., Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. Jackson T.R., J. Cell Biol. 151:627-638(2000).
ncbi acc num :
NP_055531.1
ncbi gb acc num :
NM_014716.3
ncbi pathways :
Arf6 Signaling Events Pathway (138034); Arf6 Trafficking Events Pathway (137954); Endocytosis Pathway (102279); Endocytosis Pathway (102181); NOD Pathway (198792)
uniprot summary :
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.