product summary
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company name :
MyBioSource
product type :
other
product name :
Rhodopsin (Phospho-Ser334) Antibody
catalog :
MBS859870
quantity :
0.1 mg
price :
280 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS859870 image 1
P-peptide-+ Immunohistochemistry analysis of paraffin-embedded human brain tissue using Rhodopsin (Phospho-Ser334) antibody.
product information
catalog number :
MBS859870
products type :
Antibody
products full name :
Rhodopsin (Phospho-Ser334) Antibody
products short name :
[Rhodopsin]
products name syn :
[OPN2; OPSD; opsin 2]
other names :
[rhodopsin; Rhodopsin; rhodopsin; rhodopsin; Opsin-2]
products gene name :
[RHO]
other gene names :
[RHO; RHO; RP4; OPN2; CSNBAD1; OPN2]
reactivity :
Human, Mouse, Rat
sequence length :
348
specificity :
Rhodopsin (Phospho-Ser334) antibody detects endogenous levels of Rhodopsin only when phosphorylated at serine 334.
purity :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
form :
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year.
tested application :
Immunohistochemistry (IHC), ELISA (EIA)
app notes :
IHC: 1:50-1:100. ELISA: 1:1000
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Rhodopsin around the phosphorylation site of serine 334 (D-A-SP-A-T).
other info2 :
All Sites: Human: Ser334. Mouse: Ser334. Rat: Ser334
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products references :
Edwin S. Lee, Invest. Ophthalmol. Vis. Sci., Jun 2007; 48: 2868-2876. DJ Roof, Invest. Ophthalmol. Vis. Sci., Nov 1994; 35: 4049. Angelika Schmitt, J. Exp. Biol., Apr 2005; 208: 1247-1256. Paul A. Sieving, J. Neurosci., Aug 2001; 21: 5449.
ncbi gi num :
4506527
ncbi acc num :
NP_000530.1
ncbi gb acc num :
NM_000539.3
uniprot acc num :
P08100
ncbi mol weight :
38,893 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Integrated Breast Cancer Pathway (219801); Integrin-mediated Cell Adhesion Pathway (198816); Opsins Pathway (106377)
ncbi summary :
The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. Defects in this gene are a cause of congenital stationary night blindness. [provided by RefSeq, Aug 2017]
uniprot summary :
Photoreceptor required for image-forming vision at low light intensity (PubMed:8107847, PubMed:7846071). Required for photoreceptor cell viability after birth (PubMed:2215617, PubMed:12566452). Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins (PubMed:8107847, PubMed:28524165, PubMed:26200343, PubMed:28753425). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:28524165, PubMed:26200343).
size1 :
0.1 mg
price1 :
280 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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