catalog number :
MBS859702
products full name :
PLD3 Antibody
products short name :
PLD3
other names :
Homo sapiens phospholipase D family, member 3, mRNA; Phospholipase D3; phospholipase D3; hindIII K4L homolog; choline phosphatase 3; phosphatidylcholine-hydrolyzing phospholipase D3; phospholipase D family, member 3; Choline phosphatase 3; HindIII K4L homolog; Hu-K4; Phosphatidylcholine-hydrolyzing phospholipase D3
products gene name :
PLD3
other gene names :
PLD3; PLD3; AD19; HUK4; HU-K4; PLD 3
uniprot entry name :
PLD3_HUMAN
form :
Lyophilized PLD3 antibody purified by protein affinity column containing 1% BSA and 0.02% NaN3
concentration :
100ug/200ul
storage stability :
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:1,000-1:2,000. Immunohistochemistry: 1:100-1:500. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal PLD3 (1) antibody was raised against a recombinate human PLD3 protein 162-439aa (BC036327). Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
ncbi mol weight :
54,705 Da
ncbi pathways :
Ether Lipid Metabolism Pathway (82990); Ether Lipid Metabolism Pathway (365); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); Glycerophospholipid Biosynthesis Pathway (645313); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Immune System Pathway (106386); Innate Immune System Pathway (106387); Metabolic Pathways (132956); Metabolism Pathway (477135)
ncbi summary :
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]
uniprot summary :
PLD3: Belongs to the phospholipase D family. Protein type: EC 3.1.4.4; Phospholipase; Endoplasmic reticulum; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: endoplasmic reticulum membrane; integral to membrane. Molecular Function: protein binding; phospholipase D activity. Biological Process: phosphatidylglycerol biosynthetic process; phospholipid metabolic process; glycerophospholipid biosynthetic process; lipid catabolic process. Disease: Alzheimer Disease 19