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company name :
MyBioSource
product type :
antibody
product name :
AIF1 Antibody
catalog :
MBS859403
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS859403
products type :
Antibody
products full name :
AIF1 Antibody
products short name :
AIF1
other names :
allograft inflammatory factor 1 isoform 3; Allograft inflammatory factor 1; allograft inflammatory factor 1; protein G1; interferon gamma responsive transcript; ionized calcium-binding adapter molecule 1; allograft inflammatory factor-1 splice variant Hara-1; allograft inflammatory factor 1; Ionized calcium-binding adapter molecule 1; Protein G1
products gene name :
AIF1
other gene names :
AIF1; AIF1; IBA1; IRT1; AIF-1; IRT-1; G1; IBA1; AIF-1
uniprot entry name :
AIF1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
147
form :
Lyophilized anti-AIF1 antibody purified by peptide affinity column containing 1% BSA and 0.02% NaN3
concentration :
100ug/200ul
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA titer: 1:20,000-1:80,000. Western blot analysis: 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the end user.
other info1 :
Source Note: Rabbit polyclonal AIF1 (1) antibody was raised against a peptide from C terminal residues of human AIF1 protein. Reactivity Note: Predicted: Mouse, Rat; Not yet tested in other species.
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
(1) Yamamoto,A., Ashihara,E., Nakagawa,Y. et al. Allograft inflammatory factor-1 is overexpressed and induces fibroblast chemotaxis in the skin of sclerodermatous GVHD in a murine model. Immunol. Lett. 135 (1-2), 144-150 (2011)
ncbi gi num :
14574568
ncbi acc num :
NP_001614.3
ncbi gb acc num :
NM_001623.3
uniprot acc num :
P55008
ncbi mol weight :
14,748 Da
ncbi pathways :
Spinal Cord Injury Pathway (739007)
ncbi summary :
This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
uniprot summary :
AIF1: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: perinuclear region of cytoplasm; lamellipodium; cytoplasm; perikaryon; actin filament; nucleus; cytosol; phagocytic cup. Molecular Function: actin filament binding; calcium ion binding. Biological Process: actin filament bundle formation; positive regulation of nitric oxide biosynthetic process; negative regulation of smooth muscle cell proliferation; positive regulation of smooth muscle cell proliferation; microglial cell activation; Rac protein signal transduction; cellular response to hormone stimulus; actin filament polymerization; positive regulation of muscle hyperplasia; cellular response to extracellular stimulus; positive regulation of T cell proliferation; positive regulation of protein amino acid phosphorylation; response to axon injury; phagocytosis, engulfment; response to electrical stimulus; inflammatory response; negative regulation of apoptosis
size1 :
0.1 mg
price1 :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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