antibody

MX2 Antibody

MBS858092

0.1 mg

215 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, enzyme immunoassay

Antibody

MX2 Antibody

MX2

Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; MX2; MXB; myxovirus (influenza virus) resistance 2 (mouse); Myxovirus resistance protein 2; p78-related protein; second interferon-induced protein p78

interferon-induced GTP-binding protein Mx2; Interferon-induced GTP-binding protein Mx2; interferon-induced GTP-binding protein Mx2; p78-related protein; myxovirus resistance protein 2; second interferon-induced protein p78; myxovirus (influenza virus) resistance 2; interferon-regulated resistance GTP-binding protein MXB; MX dynamin-like GTPase 2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein

MX2

MX2; MX2; MXB

MX2_HUMAN

Rabbit

Human

715

MX2 antibody detects endogenous levels of total MX2 protein.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1mg/ml

Store at -20 degree C for 1 year

Western Blot (WB), ELISA (EIA)

WB: 1:500~1:3000, ELISA: 1:20000

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human MX2. Pathway: Intermediates

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

Aebi M., Mol. Cell. Biol. 9:5062-5072(1989). Hattori M., Nature 405:311-319(2000). Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

11342664

NP_002454.1

NM_002463.1

P20592

22,105 Da

Antiviral Mechanism By IFN-stimulated Genes Pathway (530760); Cytokine Signaling In Immune System Pathway (366171); ISG15 Antiviral Mechanism Pathway (530761); Immune System Pathway (106386); Interferon Signaling Pathway (187103); Interferon Alpha/beta Signaling Pathway (187104)

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]

MX2: has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]. Protein type: G protein regulator, misc. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: cytoplasm; nuclear pore; nucleus; cytosol. Molecular Function: GTPase activity; GTP binding. Biological Process: protein transport; mRNA transport; regulation of cell cycle; metabolic process; regulation of nucleocytoplasmic transport; response to virus; cytokine and chemokine mediated signaling pathway; defense response; defense response to virus

0.1 mg

215 USD