This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
CD105(Endoglin) Antibody
catalog :
MBS857479
quantity :
0.1 ml
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot
product information
catalog number :
MBS857479
products type :
Antibody
products full name :
CD105(Endoglin) Antibody
products short name :
CD105
other names :
endoglin isoform 1; Endoglin; endoglin; transmembrane glycoprotein; cell surface MJ7/18 antigen; endoglin; Cell surface MJ7/18 antigen; CD_antigen: CD105
products gene name :
CD105
other gene names :
Eng; Eng; Endo; CD105; AI528660; AI662476; S-endoglin; Edg
uniprot entry name :
EGLN_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse
sequence length :
653
specificity :
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to mouse CD105.
purity :
Affinity purified
form :
1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
storage stability :
Store at 4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500
other info2 :
Cellular Localization: Cell membrane
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: Endoglin is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. In humans endoglin may be involved in the autosomal dominant disorder known as hereditary hemorrhagic telangiectasia type 1. This condition leads to frequent nose bleeds, telangiectases on skin and mucosa and may cause arteriovenous malformations in different organs including brain, lung, and liver.
products references :
1. "Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF-beta ligand."Ge A.Z., Butcher E.C.Gene 138:201-206(1994). "Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells."St Jacques S., Cymerman U., Pece N., Letarte M.Endocrinology 134:2645-2657(1994)
ncbi gi num :
226437647
ncbi acc num :
NP_031958.2
ncbi gb acc num :
NM_007932.2
uniprot acc num :
Q63961
ncbi mol weight :
74kDa
ncbi pathways :
TGF Beta Signaling Pathway 198393!!TGF-beta Receptor Signaling Pathway 198330!!XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway 755427
size :
0.1 ml
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

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