product summary
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company name :
MyBioSource
product type :
antibody
product name :
I kappa B-alpha (Phospho-Tyr42) Antibody
catalog :
MBS857349
quantity :
0.05 mg
price :
225 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS857349
products type :
Antibody
products full name :
I kappa B-alpha (Phospho-Tyr42) Antibody
products short name :
I kappa B-alpha
products name syn :
IkB-a (Phospho-Tyr42) Antibody
other names :
NF-kappa-B inhibitor alpha; NF-kappa-B inhibitor alpha; NF-kappa-B inhibitor alpha; ikB-alpha; IkappaBalpha; I-kappa-B-alpha; nuclear factor of kappa light chain gene enhancer in B-cells; major histocompatibility complex enhancer-binding protein MAD3; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3
other gene names :
NFKBIA; NFKBIA; IKBA; MAD-3; NFKBI; IKBA; MAD3; NFKBI; IkB-alpha; IkappaBalpha
uniprot entry name :
IKBA_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
317
specificity :
IkappaB-alpha (phospho-Tyr42) antibody detects endogenous levels of IkappaB-alpha only when phosphorylated at tyrosine 42.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
50ug/50ul
storage stability :
Store at -20 degree C for 1 year
tested application :
Immunohistochemistry (IHC)
app notes :
IHC: 1:50~1:100
other info2 :
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human IkappaB-alpha around the phosphorylation site of tyrosine 42 (E-E-YP-E-Q). All Sites: Human: Tyr42; Mouse: Tyr42; Rat: Tyr42. Pathway: NF-kappa B, Akt, Cancer/Apoptosis, Insulin/Glucose
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
B©raud C, et al. (1999) Proc Natl Acad Sci U S A 96(2): 429-434. Sundström S, et al. (2005) J Virol 79(4): 2230-2239. Liu L, et al. (1998) Mol Cell Biol 18(7): 4221-4234. Shrivastava A, et al. (1998) J Virol 72(12): 9722-9728.
ncbi gi num :
10092619
ncbi acc num :
NP_065390.1
ncbi gb acc num :
NM_020529.2
uniprot acc num :
P25963
ncbi mol weight :
35,609 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!Activated TLR4 Signalling Pathway 106400!!Activation Of NF-kappaB In B Cells Pathway 576251!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Apoptosis Modulation And Signaling Pathway 198822
ncbi summary :
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
size :
0.05 mg
price :
225 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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