catalog number :
MBS857132
products full name :
TREM1 Polyclonal Antibody
products short name :
[TREM1]
other names :
[triggering receptor expressed on myeloid cells 1 isoform 2; Triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; Triggering receptor expressed on monocytes 1; CD_antigen: CD354]
products gene name :
[TREM1]
other gene names :
[TREM1; TREM1; CD354; TREM-1; TREM-1]
reactivity :
Human, Mouse, Rat
purity :
Antigen affinity purification
form :
Each vial at least contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.1% sodium azide.
storage stability :
Store at 4 degree C or-20 degree C (with 50% glycerol); Minimize freeze-thaw cycles; Non-hazardous.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) - Other applications have not been tested.
app notes :
WB: 1:1000-2000. IHC: 1:100-200
image1 heading :
Testing Data
other info1 :
Immunogen: Recombinant human TREM1 protein.
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products description :
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
ncbi acc num :
NP_001229518.1
ncbi gb acc num :
NM_001242589.2
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); DAP12 Interactions Pathway (685549); Hemostasis Pathway (106028); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
uniprot summary :
Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.