product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
CD271 Antibody
catalog :
MBS857122
quantity :
0.1 ml
price :
290 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot
more info or order :
product information
catalog number :
MBS857122
products type :
Antibody
products full name :
CD271 Antibody
products short name :
CD271
other names :
Tumor necrosis factor receptor superfamily member 16; Tumor necrosis factor receptor superfamily member 16; tumor necrosis factor receptor superfamily member 16; NGF receptor; p75 neurotrophin receptor; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; CD_antigen: CD271
products gene name :
CD271
other gene names :
Ngfr; Ngfr; p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16; Tnfrsf16; NGF receptor
uniprot entry name :
TNR16_MOUSE
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Mouse, Rat
sequence length :
417
specificity :
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD271.
form :
Liquid
storage stability :
Store at 4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:2,000~1:5,000
other info2 :
Immunogen: affinity purified. Cellular Localization: Cell membrane
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products description :
Background: NGFR p75 or CD271 is a 75kD transmembrane glycoprotein consisting of an extracellular domain which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain, and a cytoplasmic domain. NGFR p75 displays paradoxical functions when acting alone or with other receptor proteins. Working in concert with Trk receptors, it recognizes neurotrophins and transmits trophic signals into the cell. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system.
products references :
1. "Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus."Tuffereau C., Benejean J., Blondel D., Kieffer B., Flamand A.EMBO J. 17:7250-7259(1998). 2. "Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry."Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M.J. Proteome Res. 7:5314-5326(2008)
ncbi gi num :
21264104
ncbi acc num :
Q9Z0W1.1
uniprot acc num :
Q9Z0W1
ncbi mol weight :
50kDa
ncbi pathways :
Axonal Growth Inhibition (RHOA Activation) Pathway 1000903!!Axonal Growth Stimulation Pathway 1000902!!Cell Death Signalling Via NRAGE, NRIF And NADE Pathway 1000892!!Ceramide Signalling Pathway 1000900!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!NADE Modulates Death Signalling Pathway 1000895!!NF-kB Is Activated And Signals Survival Pathway 1000899!!NFG And ProNGF Binds To P75NTR Pathway 1000891!!NRAGE Signals Death Through JNK Pathway 1000893
size :
0.1 ml
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!