MyoD (Ab-200) Antibody | MyBioSource MBS856897 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MyoD (Ab-200) Antibody

catalog :

MBS856897

quantity :

0.05 mg

price :

180 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS856897

products type :

Antibody

products full name :

MyoD (Ab-200) Antibody

products short name :

MyoD

other names :

myoblast determination protein 1; Myoblast determination protein 1; myoblast determination protein 1; myf-3; myogenic factor 3; class C basic helix-loop-helix protein 1; myogenic differentiation 1; Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3

products gene name :

MyoD

other gene names :

MYOD1; MYOD1; PUM; MYF3; MYOD; bHLHc1; BHLHC1; MYF3; MYOD; bHLHc1; Myf-3

uniprot entry name :

MYOD1_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human, Mouse, Rat

sequence length :

320

specificity :

MyoD (Ab-200) antibody detects endogenous levels of total MyoD protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

concentration :

50ug/50ul

storage stability :

Store at -20 degree C for 1 year

tested application :

Western Blot (WB)

app notes :

WB: 1:500~1:1000

other info2 :

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human MyoD around the phosphorylation site of serine 200 (A-S-SP-P-R). Pathway: Chromatin/Transcription

products categories :

Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody

products references :

Emmanuel G, et al. J. Biol. Chem., Jun 2000; 275: 18767 - 18776. Tintignac LA, et al. Mol Cell Biol. 2004 Feb; 24(4): 1809-1821. Kitzmann M, et a. Mol Cell Biol. 1999 Apr; 19(4): 3167-3176.

ncbi gi num :

23111009

ncbi acc num :

NP_002469.2

ncbi gb acc num :

NM_002478.4

uniprot acc num :

P15172

ncbi mol weight :

34,501 Da

ncbi pathways :

C-MYB Transcription Factor Network Pathway (138073); CDO In Myogenesis Pathway (160998); Developmental Biology Pathway (477129); Id Signaling Pathway (198871); Myogenesis Pathway (160997); Notch-mediated HES/HEY Network Pathway (169347); Regulation Of Nuclear SMAD2/3 Signaling Pathway (137963); Regulation Of Retinoblastoma Protein Pathway (137916); Signaling Events Mediated By HDAC Class III Pathway (137972); MiRs In Muscle Cell Differentiation Pathway (672449)

ncbi summary :

This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008]

uniprot summary :

MyoD: a transcription factor of the basic helix-loop-helix family and the myogenic factors subfamily. Involved in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. It is involved in muscle cell differentiation, and is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis. Protein type: Transcription factor; DNA-binding; RNA splicing. Chromosomal Location of Human Ortholog: 11p15.4. Cellular Component: nucleoplasm; transcription factor complex; myofibril; cytoplasm; nuclear chromatin; nucleus. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; chromatin DNA binding; protein heterodimerization activity; ubiquitin protein ligase binding; transcription coactivator activity; transcription factor binding; nuclear hormone receptor binding. Biological Process: transcription from RNA polymerase II promoter; muscle development; skeletal muscle development; skeletal muscle fiber adaptation; positive regulation of skeletal muscle regeneration; regulation of RNA splicing; myotube differentiation involved in skeletal muscle regeneration; muscle cell fate commitment; myotube cell development; skeletal muscle fiber development; cellular response to starvation; protein amino acid phosphorylation; positive regulation of myoblast differentiation; regulation of transcription from RNA polymerase II promoter; muscle cell differentiation; positive regulation of skeletal muscle fiber development; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; myoblast cell fate determination; regulation of alternative nuclear mRNA splicing, via spliceosome

size1 :

0.05 mg

price1 :

180 USD

size2 :

0.1 mg

price2 :

215

more info or order :

MyBioSource product webpage