product summary
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company name :
MyBioSource
product type :
antibody
product name :
Cytokeratin 18 Antibody
catalog :
MBS856891
quantity :
0.1 mL
price :
280 USD
clonality :
polyclonal
host :
unidentified
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS856891 image 1
Fig: Western blot analysis on Mouse liver using anti-CK18 polyclonal antibody
product information
catalog number :
MBS856891
products type :
Antibody
products full name :
Cytokeratin 18 Antibody
products short name :
[Cytokeratin 18]
other names :
[keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; keratin 18; Cytokeratin endo B; Keratin D; Cytokeratin-18; CK-18; Keratin-18; K18]
products gene name :
[CK-18]
other gene names :
[Krt18; Krt18; K18; CK18; Krt1-18; Kerd; Krt1-18; Keratin D; CK-18; K18]
clonality :
Polyclonal
isotype :
IgG
host :
unknown
reactivity :
Mouse, Rat, Human
sequence length :
423
specificity :
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of C-terminal residues of mouse CK-18.
purity :
Affinity Purified
form :
1*TBS (pH7.4), 0.5%BSA, 25% Glycerol.
storage stability :
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Western Blot (WB), Immunocytochemistry (ICC)
app notes :
WB: 1:25,000-50,000. ICC 1:200
image1 heading :
Testing Data
other info1 :
Preservative: 0.05% Sodium Azide. Cellular Localization: Cytoplasm; Perinudear region
other info2 :
Positive Control: Mouse liver
products description :
Cytokeratin 18 is an acidic keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Cytokeratin 18 exists in combination with Cytokeratin 8, a basic keratin. Hepatocellular carcinomas have been reportedly defined by the use of antibodies that recognize only Cytokeratins 8 and 18.
products references :
1. Singer P.A., Trevor K., Oshima R.G. J. Biol. Chem. 261:538-547(1986). 2. Ichinose Y., Morita T., Zhang F. etc. Gene 70:85-95(1988). 3. Dixon M.J., Robinson V., White A., Ferguson M.W. J. Anat. 183:423-438(1993).
ncbi gi num :
254540068
ncbi acc num :
NP_034794.2
ncbi gb acc num :
NM_010664.2
uniprot acc num :
P05784
ncbi mol weight :
48kDa
ncbi pathways :
Developmental Biology Pathway (1366708); EGFR1 Signaling Pathway (198278); Keratinization Pathway (1457932)
uniprot summary :
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
size1 :
0.1 mL
price1 :
280 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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