This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
alpha-Synuclein (Phospho-Tyr136) Antibody
catalog :
MBS856756
quantity :
0.05 mg
price :
225 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunocytochemistry
product information
catalog number :
MBS856756
products type :
Antibody
products full name :
alpha-Synuclein (Phospho-Tyr136) Antibody
products short name :
alpha-Synuclein
products name syn :
a-Synuclein (Phospho-Tyr136) Antibody
other names :
alpha-synuclein isoform NACP140; Alpha-synuclein; alpha-synuclein; synuclein alpha-140; non A-beta component of AD amyloid; synuclein, alpha (non A4 component of amyloid precursor); Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
other gene names :
SNCA; SNCA; PD1; NACP; PARK1; PARK4; NACP; PARK1; NACP
uniprot entry name :
SYUA_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
140
specificity :
alpha-Synuclein (phospho-Tyr136) antibody detects endogenous levels ofalpha-Synuclein only when phosphorylated at tyrosine 136.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
50ug/50ul
storage stability :
Store at -20 degree C for 1 year
tested application :
Immunofluorescence (IF)
app notes :
IF:1:100~1:200
other info2 :
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human alpha-internal Synuclein around the phosphorylation site of tyrosine 136 (Q-D-YP-E-P). Pathway: Neuroscience
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Takahashi T, et al. J Biol Chem 2003 Oct 24; 278(43): 42225-33. Ahn BH, et al. J Biol Chem 2002 Apr 05; 277(14): 12334-42. Negro A, et al. FASEB J 2002 Feb; 16(2): 210-2. Goldberg, et al. Nat. Cell Biol. 2000; 2, 115-119.
ncbi gi num :
4507109
ncbi acc num :
NP_000336.1
ncbi gb acc num :
NM_000345.3
uniprot acc num :
P37840
ncbi mol weight :
13,109 Da
ncbi pathways :
Alpha-synuclein Signaling Pathway 137913!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Amyloids Pathway 366238!!Disease Pathway 530764!!EGFR1 Signaling Pathway 198782!!Parkin-Ubiquitin Proteasomal System Pathway 700638!!Parkinson's Disease Pathway 83098!!Parkinsons Disease Pathway 705377
ncbi summary :
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
size :
0.05 mg
price :
225 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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