catalog number :
MBS856657
products full name :
eNOS (Ab-495) Antibody
products short name :
eNOS
other names :
nitric oxide synthase, endothelial isoform 1; Nitric oxide synthase, endothelial; nitric oxide synthase, endothelial; cNOS; EC-NOS; NOSIII; NOS type III; endothelial NOS; constitutive NOS; nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 (endothelial cell); Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII
products gene name :
eNOS
other gene names :
NOS3; NOS3; eNOS; ECNOS; cNOS; eNOS; NOSIII
uniprot entry name :
NOS3_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
eNOS (Ab-495) Antibody detects endogenous levels of total eNOS protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
50ug/50ul
storage stability :
Store at -20 degree C for 1 year
tested application :
Immunofluorescence (IF)
app notes :
IF:1:100~1:200
other info2 :
Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human eNOS around the phosphorylation site of threonine 495(K-K-TP-F-K). Pathway: Akt, Insulin/Glucose
products categories :
Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
products references :
Moreno H Jr.(2008)Breast Cancer Res Treat. 109(1):181-2. Lorenz M,et al.(2007)FASEB J. May;21(7):1556-64. Lin HI,et al.(2006)Transplant Proc. Sep;38(7):2203-6.
ncbi acc num :
NP_000594.2
ncbi gb acc num :
NM_000603.4
ncbi mol weight :
67,876 Da
ncbi pathways :
ACE Inhibitor Pathway 198763!!AGE/RAGE Pathway 698754!!Angiogenesis Pathway 198772!!Angiopoietin Receptor Tie2-mediated Signaling Pathway 137917!!Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Corticotropin-releasing Hormone Pathway 920957!!Disease Pathway 530764
ncbi summary :
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]