product summary
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company name :
MyBioSource
product type :
other
product name :
Keratin 18 (Ab-73) Antibody
catalog :
MBS856652
quantity :
0.05 mg
price :
170 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS856652 image 1
Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Keratin 8 (Ab-73) antibody.
product information
catalog number :
MBS856652
products type :
Antibody
products full name :
Keratin 18 (Ab-73) Antibody
products short name :
[Keratin 18]
other names :
[keratin, type II cytoskeletal 8 isoform 2; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8; keratin 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8]
products gene name :
[K18]
other gene names :
[KRT8; KRT8; K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; CYK8; CK-8; K8]
reactivity :
Human
sequence length :
483
specificity :
Keratin 8 (Ab-73) antibody detects endogenous levels of total Keratin 8 protein.
purity :
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at-20 degree C for 1 year
tested application :
Immunohistochemistry (IHC)
app notes :
IHC: 1:50-1:100
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Keratin 8 around the phosphorylation site of serine 73 (L-L-SP-P-L).
products categories :
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
products references :
Nakamichi I, et al. (2002) Mol Biol Cell; 13(10): 3441-3451. Prochasson P, et al. (2002) Nucleic Acids Res; 30(15): 3312-3322. Pankov R, et al. (1994) Proc Natl Acad Sci U S A; 91(3): 873-877. Thorey IS, et al. (1993) Mol Cell Biol; 13(11): 6742-6751.
ncbi gi num :
372466577
ncbi acc num :
NP_001243222.1
ncbi gb acc num :
NM_001256293.1
uniprot acc num :
P05787
ncbi mol weight :
56,608 Da
ncbi pathways :
EGFR1 Signaling Pathway (198782); Signaling Mediated By P38-alpha And P38-beta Pathway (138012)
ncbi summary :
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
uniprot summary :
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
size1 :
0.05 mg
price1 :
170 USD
size2 :
0.1 mg
price2 :
230
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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